Evaluation of Antioxidant, Cholinesterase Inhibitory and Antimicrobial Properties of Mentha longifolia subsp noeana and Its Secondary Metabolites

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dc.contributor.authorErtas, Abdulselam
dc.contributor.authorGoeren, Ahmet C.
dc.contributor.authorHasimi, Nesrin
dc.contributor.authorTolan, Veysel
dc.contributor.authorKolak, Ufuk
dc.date.accessioned2024-04-24T17:49:50Z
dc.date.available2024-04-24T17:49:50Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of the present study was to determine the chemical structures of the isolated compounds, the essential oil and fatty acid compositions of Mentha longifolia subsp. noeana with their biological activities. Ursolic acid (1), uvaol (2), stigmast-5-ene-3 beta-yl formate (3), stigmast-5-en-3-one (4), beta-sitosterol (5), bis(2ethylhexyl) benzene-1,2-dicarboxylate (6), hexacosyl (E)-ferulate (7) and 5-hydroxy-6,7,3',4'-tetramethoxy flavone (8) were obtained from the aerial parts. The compounds (2-4, 6, 7) were isolated for the first time from a Mentha species. Palmitic acid (40.8%) was the major component of the non-polar fraction obtained from the petroleum ether extract. Pulegone (32.3%) was the main constituent of the essential oil which exhibited strong butyrylcholinesterase inhibitory activity (77.36 +/- 0.29%), moderate antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans. The methanol extract showed 80% inhibition of lipid peroxidation, and the acetone extract possessed moderate DPPH free radical scavenging activity (60% inhibition) at 100 mu g/mL.en_US
dc.description.sponsorshipResearch Fund of Istanbul University [3603, UDP-23463]en_US
dc.description.sponsorshipThis study is a part of A.E.'s Ph.D. thesis. This work was supported by the Research Fund of Istanbul University (Project numbers: 3603, UDP-23463).en_US
dc.identifier.endpage115en_US
dc.identifier.issn1307-6167
dc.identifier.issue1en_US
dc.identifier.startpage105en_US
dc.identifier.urihttps://hdl.handle.net/11468/23010
dc.identifier.volume9en_US
dc.identifier.wosWOS:000350973300009
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherAcg Publicationsen_US
dc.relation.ispartofRecords of Natural Products
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLamiaceaeen_US
dc.subjectM. Longifolia Subsp Noeanaen_US
dc.subjectEssential Oilen_US
dc.subjectAntioxidanten_US
dc.subjectAnticholinesteraseen_US
dc.titleEvaluation of Antioxidant, Cholinesterase Inhibitory and Antimicrobial Properties of Mentha longifolia subsp noeana and Its Secondary Metabolitesen_US
dc.titleEvaluation of Antioxidant, Cholinesterase Inhibitory and Antimicrobial Properties of Mentha longifolia subsp noeana and Its Secondary Metabolites
dc.typeArticleen_US

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