Thyrotoxic periodic paralysis

dc.contributor.authorGülo?lu C.
dc.contributor.authorAldemir M.
dc.contributor.authorSö?üt Ö.
dc.contributor.authorBehçet A.
dc.date.accessioned2024-04-24T17:58:37Z
dc.date.available2024-04-24T17:58:37Z
dc.date.issued2004
dc.departmentDicle Üniversitesien_US
dc.description.abstractThyrotoxic periodic paralysis (TPP) is an uncommon disorder characterized by simultaneous thyrotoxicosis, hypokalaemia, and paralysis and is the most common acquired form of periodic paralysis. It is usually associated with low plasma potassium levels and is often precipitated by physical activity or ingestion of carbohydrates. We reported two the cases with hyperthyroidism who applied to the emergency department with episode of flaccid quadriparalyis and the literature on this subject. In the both cases, physical and laboratory examination revealed the low serum potassium levels, sinus tachycardia and ST segment depression, diffuse goiter, flaccid quadriparalysis. Potassium chloride was applied via parenteral and oral. Meanwhile antithyroid treatment (propylthiouracil and propranolol) were given to they. In first patient, it was determined that intake of high dose diclophenac sodium was the probable precipitating factor. In the both cases, paralysis began to improve in 30 minutes and had completely resolved within about 8-10 hours of admission. Thyrotoxic periodic paralysis should be taken into consideration in the differential diagnosis of all acute episodes of motor paralysis especially in young patients. Thyrothoxic periodic paralysis is treated with cautious replacement of potassium and achievement of an euthyroid state. Early diagnosis is important for planning antithyroid treatment, protecting the patient from further episodes of paralysis and avoidance of precipitating factors.en_US
dc.identifier.endpage95en_US
dc.identifier.issn1016-5134
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-4544370587en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage92en_US
dc.identifier.urihttps://hdl.handle.net/11468/24017
dc.identifier.volume16en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.relation.ispartofSENDROMen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleThyrotoxic periodic paralysisen_US
dc.title.alternativeTirotoksik periyodik paralizien_US
dc.typeReview Articleen_US

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