Thrombotic thrombocytopenic purpura associated with Graves' disease

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dc.contributor.authorAltintaş A.
dc.contributor.authorÇil T.
dc.contributor.authorAyyildiz O.
dc.contributor.authorKaplan M.A.
dc.contributor.authorMüftüoğlu E.
dc.date.accessioned2024-04-24T18:45:40Z
dc.date.available2024-04-24T18:45:40Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractThrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic hemolytic anemia and thrombocytopenia, usually accompanied by fever, renal failure and neurological deficits. TTP usually occurs in previously healthy people, but in a significant number of cases, the syndrome is associated with autoimmune disorders. We report a case of a 53 year old male patient suffering from TTP associated with Graves' disease (GD). After the diagnosis of TTP and Graves' disease plasmapheresis and antithyroid therapy were initiated. After the 15th seans of plasmapheresis, complaints were dissolved and hematologic parameters were recovered. This case draws the reader's attention to a rare condition that TTP associated with GD. Although immune thrombocytopenic purpura (ITP) and pernisious anemia must be initially considered in the event that thrombocytopenia accompanies to GD, TTP is likely in the presence of microangiopathy. The presence of microangiopathic haemolytic anemia and thrombocytopenia is sufficient for the diagnosis of TTP, thus prompt diagnosis and appropriate therapy is crucial for TTP.en_US
dc.identifier.endpage97en_US
dc.identifier.issn1306-133X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-34447509554
dc.identifier.scopusqualityQ4
dc.identifier.startpage94en_US
dc.identifier.urihttps://hdl.handle.net/11468/24771
dc.identifier.volume17en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofUHOD - Uluslararasi Hematoloji-Onkoloji Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGraves' Diseaseen_US
dc.subjectThrombocytopeniaen_US
dc.subjectThrombotic Thrombocytopenic Purpuraen_US
dc.titleThrombotic thrombocytopenic purpura associated with Graves' diseaseen_US
dc.titleThrombotic thrombocytopenic purpura associated with Graves' disease
dc.typeArticleen_US

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