Histological Changes in the Gingival Tissues of Rats Subjected to Surgical Extraction of the Adrenal Glands
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Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Medwell Online
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Hormones are specific regulatory molecules that have potent effects on the major determinants of the development and the integrity of the skeleton and oral cavity also including periodontal tissues. The aim of this study, is to investigate the effect of adrenalectomy on rat gingival tissue. Twenty-eight mature Wistar albino female and male rats divided randomly into 2 groups and in one group adrenalectomy was performed. After 21 days recovery period, Control and Experimental groups were sacrificed under Ketamin HCi anesthesia and clinical and histological observations were made. Microscopic findings, revealed significant changes in adrenalectomized rats. Hypertrophy and thickness of gingival epitelium was apparent in the gingival epithelium of ADX group. Increase in mitotic activity in stratum basale layer of gingival epitelium and increase in keratinisaton layer were observed in adrenalectomized rats. A decrease in collagen fibrils and irregularity of papilla was seen in adrenalectomized rats. Our findings demonstrate the importance of adrenal glands in the development of gingival tissue and suggest that adrenal glands deficiency is one mechanism, by which gingival disorder susceptibility may be increased.
Açıklama
Anahtar Kelimeler
Gingival Tissue, Adrenalectomy, Rat, Histological Changes, Weight Of Liver, Kidney And Hypophysis
Kaynak
Journal of Animal and Veterinary Advances
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
8
Sayı
3
