Does detection of follicle rupture affect success in intrauterine insemination cycles? A tertiary center experience

dc.authorid0000-0001-5437-7987en_US
dc.authorid0000-0001-6911-2359en_US
dc.authorid0000-0002-3285-9990en_US
dc.authorid0000-0001-7062-3076en_US
dc.authorid0000-0002-8905-1909en_US
dc.contributor.authorAbide, Çiğdem Yayla
dc.contributor.authorDevranoğlu, Belgin
dc.contributor.authorPeker, Nurullah
dc.contributor.authorÇöğendez, Ebru
dc.contributor.authorKumru, Pınar
dc.date.accessioned2023-05-22T07:02:11Z
dc.date.available2023-05-22T07:02:11Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalıen_US
dc.description.abstractObjective: The aim of this study is to investigate the effect of intrauterine insemination (IUI) performed simultaneously with ultrasound detected follicular rupture during biological reproduction window on pregnancy rates in patients with unexplained infertility undergoing ovulation induction (OI) cycles with gonadotropins. Material and Methods: Three-hundred and twenty-five patients with unexplained infertility were included in this prospective cohort study, who received recombinant follicular stimulating hormone (75–150 IU/day) or Human Menopausal Gonadotropin starting from the 2nd to 3rd days of the cycle. IUI was carried out with ultrasonographic monitoring of the follicles. The presence of free fluid within the Douglas pouch, detection of corpus luteum, and/or loss of the dominant follicle was interpreted as follicular rupture. Pregnancy rates with or without follicular rupture were compared after 14 days. Results: Among those with follicular rupture, the time between administration of recombinant hCG and IUI was significantly longer as compared to those without follicular rupture (p<0.001). β hCG was positive at 14 days after IUI in 19.01% (31/163) and 13.92% (22/158) of the cases with or without follicular rupture, respectively. The difference in pregnancy rates was not significant (p=0.219). Conclusion: IUI simultaneously performed with ultrasound-detected follicular rupture in OI cycles with gonadotropins does not increase pregnancy rate.en_US
dc.identifier.citationAbide, Ç.Y., Devranoğlu, B., Peker, N., Çöğendez, E. ve Kumru, P. (2023). Does detection of follicle rupture affect success in intrauterine insemination cycles? A tertiary center experience. Zeynep Kamil Medical Journal, 54(1), 1-6.en_US
dc.identifier.doi10.14744/zkmj.2022.65391
dc.identifier.endpage6en_US
dc.identifier.issn2757-8062
dc.identifier.issue1en_US
dc.identifier.startpage1en_US
dc.identifier.trdizinid1165062
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1165062
dc.identifier.urihttps://hdl.handle.net/11468/11840
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1165062
dc.identifier.volume54en_US
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorPeker, Nurullah
dc.language.isoenen_US
dc.publisherKare Publishingen_US
dc.relation.ispartofZeynep Kamil Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFollicle ruptureen_US
dc.subjectInfertilityen_US
dc.subjectIntrauterine inseminationen_US
dc.subjectOvulation inductionen_US
dc.titleDoes detection of follicle rupture affect success in intrauterine insemination cycles? A tertiary center experienceen_US
dc.titleDoes detection of follicle rupture affect success in intrauterine insemination cycles? A tertiary center experience
dc.typeArticleen_US

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