Cranial Involvement in a Follicular Lymphoma Patient with Systemic Complete Remission After Yttrium-90-Ibritumomab-Tiuxetan Treatment: Scientific Letter

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dc.contributor.authorCil, Timucin
dc.contributor.authorAltintas, Abdullah
dc.contributor.authorPasa, Semir
dc.contributor.authorKilinc, Ilhan
dc.contributor.authorIsikdogan, Abdurrahman
dc.date.accessioned2024-04-24T17:40:28Z
dc.date.available2024-04-24T17:40:28Z
dc.date.issued2008
dc.departmentDicle Üniversitesien_US
dc.description.abstractNon-Hodgkin's lymphoma is a heterogeneous group of lymphoproliferative disorders with varying patterns of behavior and treatment responses. Advances in understanding of tumor biology have made it possible to exploit novel treatment strategies such as monoclonal antibodies and their conjugation with radioimmunotherapy was recommended in patients with first relapse of low-grade lymphomas such as follicular lymphoma after rituximab containing chemotherapy. Treatment with radioimmunotherapy such as yttrium-90-ibritumomab-tiuxetan utilizes a monoclonal anti-CD20 antibody to deliver beta-emitting yttium-90 to the malignant B-cells. Clinical trials have demonstrated its efficacy, which is largely independent of the intrinsic activity of the anti-CD20 antibody. Relapses of nodal lymphomas usually occur in extra lymphoid areas. Central nervous system (CNS) involvement develops in less than 1% of patients with lymphomas. Herein, we are presenting a rare case of CNS involvement of follicular lymphoma in a patient who has achieved systemic complete remission after yttrium-90-ibritumomab treatment.en_US
dc.identifier.endpage955en_US
dc.identifier.issn1300-0292
dc.identifier.issue6en_US
dc.identifier.startpage953en_US
dc.identifier.urihttps://hdl.handle.net/11468/21814
dc.identifier.volume28en_US
dc.identifier.wosWOS:000262383600024
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherOrtadogu Ad Pres & Publ Coen_US
dc.relation.ispartofTurkiye Klinikleri Tip Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLymphomaen_US
dc.subjectLymphoma, Follicularen_US
dc.titleCranial Involvement in a Follicular Lymphoma Patient with Systemic Complete Remission After Yttrium-90-Ibritumomab-Tiuxetan Treatment: Scientific Letteren_US
dc.titleCranial Involvement in a Follicular Lymphoma Patient with Systemic Complete Remission After Yttrium-90-Ibritumomab-Tiuxetan Treatment: Scientific Letter
dc.typeArticleen_US

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