Immunohistochemical detection of estrogen and progesteron receptors in the bovine uterus and their relation to serum sex steroid hormone levels during the follicular and luteal phase

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dc.contributor.authorGuney Saruhan B.
dc.contributor.authorSagsoz H.
dc.contributor.authorKetani M.A.
dc.contributor.authorAkbalik M.E.
dc.contributor.authorOzyurtlu N.
dc.date.accessioned2024-04-24T17:59:00Z
dc.date.available2024-04-24T17:59:00Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn this study, we tried to show the expression patterns of the steroid receptors in the bovine endometrium during the follicular and luteal phase. Samples of both uterus and blood were obtained from 30 adult, healty bovine at the moment of slaughter at a local slaughterhouse. Immunohistochemistry was performed by using rabbit polyclonal antibodies against the estrogen receptor (ER) and mouse monoclonal antibodies against the progesterone receptor (PR). In general, most of the uterine cells were stained positive but with a different intensity. During follicular phase, both ER and PR were obviously strong in the epithelia and the myometrium. For the glandular epithelium (GE), all GE cells were stained positive for ER and PR. When we compared both receptors during lutheal phase, a stronger intensity was observed in all compartments for PR, especially in the myometrium and surface-glandular epithelium. To summarize, the results from this study showed that both ER and PR might be regulated by the same mechanisms in some compartments and at specific stages of the oestrous cycle, and that each compartment of the uterus had a different expression of ER and PR which could accord with their different roles in reproductive physiology.en_US
dc.identifier.endpage454en_US
dc.identifier.issn1300-6045
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-70349268198en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage447en_US
dc.identifier.urihttps://hdl.handle.net/11468/24191
dc.identifier.volume15en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBovine Uterusen_US
dc.subjectEstrogen Receptoren_US
dc.subjectImmunohistochemistryen_US
dc.subjectProgesterone Receptoren_US
dc.titleImmunohistochemical detection of estrogen and progesteron receptors in the bovine uterus and their relation to serum sex steroid hormone levels during the follicular and luteal phaseen_US
dc.title.alternativeİnek uterusunda folliküler ve luteal fazda östrojen ve progesteron reseptörlerinin i?mmunohistokimyasal olarak belirlenmesi ve serum steroidleri ile i?lişkisien_US
dc.typeArticleen_US

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