Remifentanil and droperidol administration for monitored anaesthesia care
[ X ]
Tarih
2002
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this prospective randomised study, it was aimed to evaluate which dose of remifentanil applied via patient controlled analgesia (PCA) was proper for monitored anaesthesia care during extracorporeal shock wave lithotripsy in patients received droperidol as pretreatment [A1]. Droperidol (20 ?g/kg) was administered intravenously, and then the subjects were randomly assigned to one of three groups. Group I (n=20) received a remifentanil 1 ?g/kg as loading and bolus dose and infusion of 0.01 ?g/kg/min; Group II (n=20) received a remifentanil 0.5 ?g/kg as loading and bolus dose and infusion of 0.05 ?g/kg/min; Group III (n=20) received a remifentanil 0.1 ?g/kg as loading and bolus dose and infusion of 0.1 ?g/kg/min. Two minutes after applying loading dose with PCA, ESWL procedure was started. Hemodynamic and respiratory data, adverse effects such as nausea, vomiting, dizziness, level of pain and sedation were recorded. The end of ESWL procedure, consumption of remifentanil was recorded. After satisfactions of patients were registered, the patients fully recovered discharged from hospital. In Group I and Group II, level of pain was significantly lower than Group III (p<0.05). In Group I, frequency of respiratory and hemodynamic depression was higher than other group. However, In Group III, incidences of nausea, vomiting and dizziness were higher than other group. Satisfactions of patients were statistically highest in Group II. Moreover, consumption of remifentanil was lowest in Group II. No difference was among three group in discharge time from hospital. We concluded that for monitored anaesthesia care during ESWL, remifentanil at loading and bolus dose of 0.5 ?g/kg and infusion rate of 0.05 ?g/kg/min provided effective analgesia and had low incidence of adverse effects in patients had been received droperidol.
Açıklama
Anahtar Kelimeler
Droperidol, Eswl, Monitored Anaesthesia Care, Remifentanil
Kaynak
Turk Anesteziyoloji ve Reanimasyon
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
30
Sayı
6
