Use of the neutrophil to lymphocyte ratio compare crp for the early prediction of acute pancreatitis severity?

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dc.contributor.authorBozdağ, Zübeyir
dc.contributor.authorÜlger, Burak Veli
dc.contributor.authorZengin, Yılmaz
dc.contributor.authorArıkanoğlu, Zülfü
dc.contributor.authorTürkoğlu, Ahmet
dc.contributor.authorGümüş, Metehan
dc.contributor.authorYılmaz, Edip Erdal
dc.date.accessioned2024-04-24T19:11:21Z
dc.date.available2024-04-24T19:11:21Z
dc.date.issued2018
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: To determine the usefulness of the neutrophil to lymphocyte ratio (NLR) as a diagnostic tool for the early detection and prediction of acute pancreatitis (AP) severity compared with that of C-reactive protein (CRP).Material and Methods: The medical records of 464 patients hospitalized with AP between 2006 and 2014 were reviewed. The patients were classified into two groups: severe AP (SAP) and mild/moderate AP groups. Lymphocyte and neutrophil counts and CRP levels at the time of admission were noted.Results: Out of the total number of patients (n = 464), 67 had severe AP. The median NLR was significantly higher in the SAP group (median of 11.1) than in the mild/moderate AP group (median of 6.9) (p < 0.0001). The sensitivity and specificity of NLR were 83.6% and 49.4%, respectively, with a cut-off value of 6.8 and an AUC of 0.68. CRP levels were also significantly higher in the SAP group (median of 189 mg/L) than in the mild/moderate AP group (median of 53.5 mg/L) (p < 0.0001). The sensitivity and specificity of theCRP values were 83.6 % and 74.9 %, respectively, with a cut-off value of 113 mg/L and an AUC of 0.83.Conclusion: The NLR was significantly higher in patients with severe AP. However, CRP measurement was superior to NLR as an early predictor of severe disease.en_US
dc.identifier.doi10.5455/annalsmedres.2018.05.082
dc.identifier.endpage454en_US
dc.identifier.issn2636-7688
dc.identifier.issue3en_US
dc.identifier.startpage450en_US
dc.identifier.trdizinid285689
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2018.05.082
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/285689
dc.identifier.urihttps://hdl.handle.net/11468/27940
dc.identifier.volume25en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleUse of the neutrophil to lymphocyte ratio compare crp for the early prediction of acute pancreatitis severity?en_US
dc.titleUse of the neutrophil to lymphocyte ratio compare crp for the early prediction of acute pancreatitis severity?
dc.typeArticleen_US

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