Post- pemphigus acanthomata

Pemphigus is a group of vesiculobullous disorders in which the blisters usually heal with hyperpigmentation. The appearance of acanthomata at sites of previous blisters has been noted in some cases. We described a 48-year- old patient with pemphigus vulgaris, who was treated with systemic steroids, and who developed acanthomata on the sites of some healed blisters. The acanthomata were seen as verrucous lesions at sites of healed blisters, and were observed in the trunk. Histopathology of lesions showed suprabasal cleft associated with hyperkeratosis, acanthosis, and papillomatosis. Acantholytic cells were seen intraepidermally within the cleft. Acanthomata occurring in patients whose pemphigus is in remission is not uncommon. Since post- pemphigus acanthomata shows histopathologic activity, these cases should be carefully followed-up.