In vitro efficiency of ertapenem among escherichia coli strains isolated from clinical specimens

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dc.contributor.authorTekin A.
dc.contributor.authorDeveci Ö.
dc.contributor.authorDal T.
dc.contributor.authorTekin R.
dc.contributor.authorBacalan F.
dc.contributor.authorAkpolat N.
dc.date.accessioned2024-04-24T18:43:42Z
dc.date.available2024-04-24T18:43:42Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn this study, in vitro efficiency of ertapenem and extanded-spectrum beta-lactamase (ESBL) producing among Escherichia coli strains isolated from clinical specimens were investigated. 334 E. coli strains isolated from clinical specimens that sent to Dicle University Hospital clinical microbiology laboratory between December 2010 and August 2011 were included in this study. Identification of isolates was performed by conventional methods and a fully automated microbiology system. Antimicrobial susceptibility testing of strains was performed by Kirby- Bauer's disc diffusion method and E-test method. Double-disk synergy method was used for the detection of ESBL-producing. 334 E. coli strains were isolated from clinical specimens as 233 (69.8%) urine, 55 (16.4%) blood, 32 (9.6%) wound swabs and 14 (4.2%) others. In 177 (53%) from 334 E. coli strains were determined the ESBL activity. Ertapenem sensitivity rate among strains was determined as 93.4%. Although there was no resistance to ertapenem in ESBL-non-producing strains, ertapenem resistance rate was found as 12.4% in ESBL-producing strains. The high resistance rate for ertapenem in ESBL-producing strains according to the ESBL-non-producing strains was found to be statistically significant (p<0.001). In the light of present study, we think as the better option of ertapenem which has got a high sensitivity rate in the treatment with antimicrobial agents of infections caused by ESBL-producing E. coli strains at least in our hospital.en_US
dc.identifier.endpage13en_US
dc.identifier.issn1306-8814
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84878395810en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage10en_US
dc.identifier.urihttps://hdl.handle.net/11468/24300
dc.identifier.volume7en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofAnatolian Journal of Clinical Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectErtapenemen_US
dc.subjectEscherichia Colien_US
dc.subjectExtanded-Spectrum Beta-Lactamaseen_US
dc.subjectIn Vitroen_US
dc.subjectMicrobial Sensitivity Testen_US
dc.titleIn vitro efficiency of ertapenem among escherichia coli strains isolated from clinical specimensen_US
dc.title.alternativeKlinik örneklerden izole edilen escherichia coli suşlarinda ertapenemin in vitro etkinliğien_US
dc.typeArticleen_US

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