Investigation of Mean Platelet Volume and Platelet Count in the Blood of Patients with Migraine

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dc.contributor.authorVarol, Sefer
dc.contributor.authorAkil, Esref
dc.contributor.authorCevik, Mehmet Ugur
dc.contributor.authorCelepkolu, Tahsin
dc.contributor.authorYucel, Yavuz
dc.contributor.authorTanriverdi, Mehmet Halis
dc.contributor.authorAluclu, Mehmet Ufuk
dc.date.accessioned2024-04-24T17:24:30Z
dc.date.available2024-04-24T17:24:30Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Mean platelet volume (MPV) is an indicator for platelet function and activation. Studies researching MPV and platelet level on the patients with migraine are insufficient. In this study, we aimed to find a difference in MPV and platelet count in individuals with migraine compared to healthy controls, which are indicators for platelet activation. Material and Method: We recruited 193 patients (female/male: 128/65, average age: 31.66 +/- 9.01) who are referred to the Neurology Clinic of Dicle University, Faculty of Medicine between January 2010 and January 2012 and have been diagnosed with migraine according to 2004 diagnostic criteria of International Headache Society (IHS) and 119 healthy individuals (female/male: 73/46, averge age: 32.27 +/- 9.88) who are referred to the Family Practice Clinic and Blood Bank. We compared MPV and platelet counts between the patients with migraine and healthy controls. Both groups were similar in terms of age and gender. Results: A statistically insignificant increase was found in MPV in patients with migraine (7.98 +/- 1.34 fL) when compared to the control group (7.85 +/- 0.96 fL) (p=0.34). Platelet levels were significantly lower in patients with migraine (367.6 +/- 74.2) than the platelet levels of the control group (286.9 +/- 68.3) (p=0.02). Discussion: We found lower platelet levels in the patients with migraine compared to the control group. There was also statistically insignificant increase in MPV in patients with migraine, suggesting that these findings may indicate an insignificant platelet activation in patients with migraine. New prospective studies are needed on this subject.en_US
dc.identifier.doi10.4274/Tnd.88156
dc.identifier.endpage92en_US
dc.identifier.issn1301-062X
dc.identifier.issn1309-2545
dc.identifier.issue3en_US
dc.identifier.startpage90en_US
dc.identifier.urihttps://doi.org/10.4274/Tnd.88156
dc.identifier.urihttps://hdl.handle.net/11468/19707
dc.identifier.volume19en_US
dc.identifier.wosWOS:000217541300003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherTurkish Neurological Socen_US
dc.relation.ispartofTurkish Journal of Neurology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMigraineen_US
dc.subjectPlatelet Activationen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectPlatelet Counten_US
dc.titleInvestigation of Mean Platelet Volume and Platelet Count in the Blood of Patients with Migraineen_US
dc.titleInvestigation of Mean Platelet Volume and Platelet Count in the Blood of Patients with Migraine
dc.typeArticleen_US

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