Intrahepatic cholestasis of pregnancy: Is fetoplacental doppler ultrasound useful in the diagnosis and follow-up?

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dc.authorid0000-0002-9178-7843en_US
dc.contributor.authorToprak, Veysel
dc.contributor.authorKafadar, Mehmet Tolga
dc.date.accessioned2021-06-01T11:42:59Z
dc.date.available2021-06-01T11:42:59Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalıen_US
dc.descriptionWOS:000645097300019
dc.description.abstractAim: In this study, we aimed to examine whether Doppler ultrasonography (USG) is an important diagnostic tool for fetal follow-up in case of obstetric cholestasis. Material and Methods: This study included 50 patients diagnosed with obstetric cholestasis and 39 pregnant women turning up for their regular pregnancy follow-up. Pregnants were diagnosed according to definition, symptoms, and laboratory findings. Biochemical tests, bile acid test, upper abdominal USG, Non-Stress Test (NST), obstetric USG, amniotic fluid test, and fetoplacental Doppler USG were performed on all patients. Systole/Diastole (S/D) ratio of Umbilical artery (UA) and Middle cerebral artery (MCA)s, delivery types of patients, weight at birth, Apgar scores, and the existence of meconium were separately recorded. Results: The mean age of the patients with obstetric cholestasis was 26.6 years, while in the control group it was 25.1 years (p = 0.176). No statistical difference was identified with regard to the average of (UA and MCA)/(S/D) ratio of both patient groups. In terms of delivery type, patients' UA and MCA S/D ratio averages were not statistically significant. There was no statistical link between cholestasis story in previous pregnancies, cholestasis in the current pregnancy, bile acid, and high ALP and baby's gender. Discussion: Intrahepatic cholestasis of pregnancy is also a reversible form of cholestasis and it usually emerges in the late pregnancy period and continues until birth. In this study, it was detected that fetoplacental Doppler USG, which is used as a diagnostic tool for obstetric cholestasis, has a low level of predictivity. During our study, Doppler USG use in obstetric cholestasis diagnosis and follow-up was not effective.en_US
dc.identifier.citationToprak, V. ve Kafadar, M.T. Intrahepatic cholestasis of pregnancy: Is fetoplacental doppler ultrasound useful in the diagnosis and follow-up? Annals of Clinical and Analytical Medicine, 12(1), 87-91.en_US
dc.identifier.doi10.4328/ACAM.20203
dc.identifier.endpage91en_US
dc.identifier.issn2667-663X
dc.identifier.issue1en_US
dc.identifier.startpage87en_US
dc.identifier.urihttp://www.bayrakol.org/en/2021/january2021/original-article/item/2384-intrahepatic-cholestasis-of-pregnancy-is-fetoplacental-doppler-ultrasound-useful-in-the-diagnosis-and-follow-up
dc.identifier.urihttps://hdl.handle.net/11468/7009
dc.identifier.volume12en_US
dc.identifier.wosWOS:000645097300019
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorKafadar, Mehmet Tolga
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals of Clinical and Analytical Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCholestasisen_US
dc.subjectDiagnosisen_US
dc.subjectDoppler ultrasounden_US
dc.subjectFetalen_US
dc.subjectPregnancyen_US
dc.titleIntrahepatic cholestasis of pregnancy: Is fetoplacental doppler ultrasound useful in the diagnosis and follow-up?en_US
dc.titleIntrahepatic cholestasis of pregnancy: Is fetoplacental doppler ultrasound useful in the diagnosis and follow-up?
dc.typeArticleen_US

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