The role of hemogram parameters in predicting the severity of preeclampsia

dc.authoridSizer, Mulaim/0000-0003-4864-7287
dc.contributor.authorSizer, Mulaim
dc.contributor.authorPeker, Nurullah
dc.contributor.authorGunduz, Reyhan
dc.contributor.authorEvsen, Mehmet Siddik
dc.contributor.authorSunar, Nebahat
dc.contributor.authorGunsel, Hamdin
dc.date.accessioned2025-02-22T14:08:37Z
dc.date.available2025-02-22T14:08:37Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: The purpose of this study was to examine the significance of hemogram parameters in predicting preeclampsia and/or preeclampsia severity in patients with pre -diagnosis of preeclampsia. Material and Methods: The study was retrospective and comprised 198 patients with preeclampsia, 158 with severe preeclampsia and 40 with non -severe preeclampsia, as well as 126 pregnant women who had a healthy pregnancy as the control group. From the hemogram parameters, platelet count (PLT), neutrophil count, mean platelet volume (MPV), mean erythrocyte volume (MCV), leukocyte count and neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (TLR) and platelet/neutrophil ratio (TNR) were calculated. The pregnant women included in the study were compared in terms of these parameters. Results: While there was no statistically significant difference between the groups in the statistical analysis of MCV, MPV, NLR, and TNO, which are the parameters studied in PE groups with and without severe features, a statistically significant difference was found in these parameters between the control group and the preeclampsia group. At the TNO 35,1250 cut-off value, the sensitivity was 83.8 %, the specificity was 41.3 %, the positive predictive value was 69.17 %, and the negative predictive value was 61.90 %, and it was found that this value predicted the presence of PE as 69%. Discussion: In this study, we discovered that MPV, MCV, TNO, and NLO levels differed significantly between the PE and control groups. However, the sensitivity and specificity rates of these parametria in the detection of preeclampsia are far below significant values.en_US
dc.identifier.doi10.4328/ACAM.22173
dc.identifier.endpage372en_US
dc.identifier.issn2667-663X
dc.identifier.issue5en_US
dc.identifier.startpage369en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.22173
dc.identifier.urihttps://hdl.handle.net/11468/29522
dc.identifier.volume15en_US
dc.identifier.wosWOS:001222910000007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectHemogramen_US
dc.subjectMCVen_US
dc.subjectMPVen_US
dc.subjectNLRen_US
dc.subjectPLRen_US
dc.subjectPNRen_US
dc.subjectPreeclampsiaen_US
dc.titleThe role of hemogram parameters in predicting the severity of preeclampsiaen_US
dc.typeArticleen_US

Dosyalar