Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy

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dc.contributor.authorBulut, Mahmut
dc.contributor.authorAltindag, Abdurrahman
dc.contributor.authorDeveci, Zeliha
dc.contributor.authorKaya, M. Cemal
dc.contributor.authorBulbl, Feridun
dc.contributor.authorTaskin, Abdullah
dc.contributor.authorKocamer, Sengul
dc.date.accessioned2024-04-24T17:27:40Z
dc.date.available2024-04-24T17:27:40Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractElectroconvulsive (ECT) is one of the most efficacious choice in the treatment of bipolar disorder. There is no study conducted on human being investigating the effect of ECT on oxidative balance in bipolar disorder. In the present study, we aimed to evaluate the oxidative parameters on bipolar inpatients who is treated with ECT and pharmacotherapy. 31 bipolar inpatients in psychiatry department of Gaziantep University and 35 healty volunteeers were included in the study. Total Antioxidant Status (TAS), Total Oxidant Status (TOS) of serum samples were measured and Oxidative Stress Index (OSI) were counted in Harran University Biochemistry Laboratory. In all patient group, bipolar manic episode and depressive episode patients; before ECT and after ECT there was no significant difference for oxidative parameters. Before ECT, TAS levels in bipolar depressive episode patients were significantly lower than the control group (z=-2.614, p= 0.009). But after ECT, there was no difference between these two groups (z=-1.558, p> 0.05). Before ECT, TOS levels in bipolar manic episode patients were significantly higher than the control group (z=-2.598, p= 0.009); after ECT, there was no difference between these two groups (z=-0.910, p> 0.05). Finally, when compared with controls, in bipolar depressive episode patients TAS levels were increased with ECT and pharmacotheraphy and in bipolar manic episode patients TOS levels were decreased. For more comprehensive results new studies are needed.en_US
dc.identifier.doi10.5455/jmood.20130402053002
dc.identifier.endpage99en_US
dc.identifier.issn2146-1473
dc.identifier.issn2146-2380
dc.identifier.issue3en_US
dc.identifier.startpage93en_US
dc.identifier.urihttps://doi.org/10.5455/jmood.20130402053002
dc.identifier.urihttps://hdl.handle.net/11468/20126
dc.identifier.volume3en_US
dc.identifier.wosWOS:000421350500001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotren_US
dc.publisherYerkure Tanitim & Yayincilik Hizmetleri A Sen_US
dc.relation.ispartofJournal of Mood Disorders
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBipolar Disorderen_US
dc.subjectElectroconvulsive Therapyen_US
dc.subjectOxidative Parametersen_US
dc.subjectCombined Treatmenten_US
dc.subjectOxidative Parametersen_US
dc.titleOxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapyen_US
dc.titleOxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy
dc.typeArticleen_US

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