Hereditary thrombophilic risk factors in patients with deep venous thrombosis

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dc.contributor.authorAltintaş A.
dc.contributor.authorÇil T.
dc.contributor.authorKaplan M.A.
dc.contributor.authorYurt M.
dc.contributor.authorBatun S.
dc.date.accessioned2024-04-24T18:43:37Z
dc.date.available2024-04-24T18:43:37Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe prevalence of hereditary risk factors for deep venous thrombosis (DVT) varies greatly in different parts of the world. Factor V Leiden (FVL) and prothrombin G 20210A (FT G20210A) are the most common genetic defects leading to venous thrombosis. The aim of this study was to investigate the frequency of FVL and PT G20210A mutations in adult patient with DVT in our region. Between September 2001 and August 2006, 52 patients with documented venous thrombosis were investigated in our center for the presence of FVL and PT G20210A mutations. Fourteen of 52 patients with thrombosis (%26.9) were detected to have a FVL mutation. The PT G20210A mutation was detected in 6 (%11) of the 52 patients. Our findings reveal that FVL and PT G20210A mutations are significantly higher in patients with DVT than in the healty population in the southeast of Turkey.en_US
dc.identifier.endpage69en_US
dc.identifier.issn1306-133X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-34447559762en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage65en_US
dc.identifier.urihttps://hdl.handle.net/11468/24217
dc.identifier.volume17en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.relation.ispartofUHOD - Uluslararasi Hematoloji-Onkoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDeep Vein Thrombosisen_US
dc.subjectFactor V Leidenen_US
dc.subjectProthrombin G20210aen_US
dc.titleHereditary thrombophilic risk factors in patients with deep venous thrombosisen_US
dc.title.alternativeDerin ven trombozu olgularinda herediter trombofilik risk faktörlerien_US
dc.typeArticleen_US

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