AN INVESTIGATION OF THE ACE INHIBITORY ACTIVITY, ANTIOXIDANT CAPACITY, AND PHYTOCHEMICAL CONSTITUENTS OF POLAR AND NON-POLAR EXTRACTS OF ZIZIPHUS JUJUBA FRUIT: STATISTICAL SCREENING THE MAIN COMPONENTS RESPONSIBLE FOR BIOACTIVITY

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dc.contributor.authorFındık, Bahar Tuba
dc.contributor.authorYıldız, Hilal
dc.contributor.authorBirişçi, Esma
dc.contributor.authorYiğitkan, Serkan
dc.contributor.authorYılmaz, Pelin Köseoğlu
dc.contributor.authorErtaş, Abdulselam
dc.date.accessioned2025-02-22T14:18:01Z
dc.date.available2025-02-22T14:18:01Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractHerein, the angiotensin I-converting enzyme (ACE) inhibitory activity, antioxidant capacity, total polyphenol contents (TPC), and phytochemical profiles of polar and non-polar extracts of dried Ziziphus jujuba fruits were investigated, along with the statistical determination of the main components responsible for ACE inhibitory activity. The non-polar extract expressed the strongest ACE inhibitory activity (99.81%) among the extracts. The non-polar extract also exhibited the highest DPPH scavenging activity (IC50 of 30.63), linoleic acid/β-carotene bleaching capacity (89.31%), and TPC (59.47 mg GAE/g). The phenolic profiles of the extracts were identified by LC-MS/MS, and the presence of seven triterpenoid species in the extracts was examined using GC-MS techniques. The principal constituents included 19 phenolics, 2 organic acids, and 4 triterpenoids. A Pearson correlation and principal component analysis were conducted to find the correlation between individual phenolic compounds and ACE inhibitory activity.en_US
dc.identifier.doi10.15237/gida.GD24028
dc.identifier.endpage566en_US
dc.identifier.issn1300-3070
dc.identifier.issn1309-6273
dc.identifier.issue3en_US
dc.identifier.startpage554en_US
dc.identifier.trdizinid1244984en_US
dc.identifier.urihttps://doi.org/10.15237/gida.GD24028
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1244984
dc.identifier.urihttps://hdl.handle.net/11468/30207
dc.identifier.volume49en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofGIDAen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_TR_20250222
dc.subjectZiziphus jujubaen_US
dc.subjectprincipal component analysisen_US
dc.subjectantioxidant capacityen_US
dc.subjectPearson correlationen_US
dc.subjectACE inhibitory activityen_US
dc.subjectphytochemical profileen_US
dc.titleAN INVESTIGATION OF THE ACE INHIBITORY ACTIVITY, ANTIOXIDANT CAPACITY, AND PHYTOCHEMICAL CONSTITUENTS OF POLAR AND NON-POLAR EXTRACTS OF ZIZIPHUS JUJUBA FRUIT: STATISTICAL SCREENING THE MAIN COMPONENTS RESPONSIBLE FOR BIOACTIVITYen_US
dc.typeArticleen_US

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