The anti-candidal activity of salvia verticillata subsp. verticillata against several candida species

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dc.authorid0000-0002-4090-7227en_US
dc.authorid0000-0001-9446-8584en_US
dc.authorid0000-0002-3557-1677en_US
dc.contributor.authorIbrahim, Mahdi Hashim
dc.contributor.authorSurchi, Badr Qader
dc.contributor.authorAzeez, Safiya A.
dc.contributor.authorAlma, M. Hakkı
dc.contributor.authorKireçci, Ekrem
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorUğuz, Metin Tansu
dc.date.accessioned2025-02-21T06:42:11Z
dc.date.available2025-02-21T06:42:11Z
dc.date.issued2024en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractThe examination of Salvia verticillata extract encompassed an exploration of its anti-Candida properties, phytochemical composition, antioxidant activity, and the quantification of total tannins. The use of ethanol as a solvent yielded the highest extraction efficiency at 26.1%. The plant exhibited a substantial tannin content of 6.5 mg/kg, signifying a noteworthy concentration. The inhibitory zones against Candida tropicalis reached a minimum diameter of 17.6 mm, while Candida guilliermondii displayed the most significant inhibition with a zone diameter of 21.8 mm. The minor inhibitory concentration (MIC) findings for all Candida species ranged from 6.25 to 12.5 g/ml. In the case of Candida guilliermondii, the synthetic antifungal activity FLU/25 demonstrated a maximal inhibition zone measuring 39.30 mm. Additionally, the maximum antioxidant activity, recorded at 0.3 ml, reached a value of 98.65. Phytochemical screening unveiled elevated concentrations of phenols and flavonoids, with malic acid (1901.1 g/g), hesperidin (302.4 g/g), and rosmarinic acid (30619.93 g/g) all experiencing an increase in concentration. These findings provide a comprehensive understanding of the diverse bioactive components and properties associated with Salvia verticillata extract.en_US
dc.identifier.citationIbrahim, M. H., Surchi, B. Q., Azeez, S. A., Alma, M. H., Kireçci, E., Yılmaz, M. A. ve diğerleri. (2024). The anti-candidal activity of salvia verticillata subsp. verticillata against several candida species. Zanco Journal of Pure and Applied Sciences, 36(5), 12-23.en_US
dc.identifier.endpage23en_US
dc.identifier.issn2218-0230
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85209915814
dc.identifier.scopusqualityN/A
dc.identifier.startpage12en_US
dc.identifier.urihttps://zancojournal.su.edu.krd/index.php/JPAS/article/view/1643/1206
dc.identifier.urihttps://hdl.handle.net/11468/29480
dc.identifier.volume36en_US
dc.indekslendigikaynakScopus
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.language.isoenen_US
dc.publisherSalahaddin Universityen_US
dc.relation.ispartofZanco Journal of Pure and Applied Sciences
dc.relation.isversionof10.21271/ZJPAS.36.5.2en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnti-candida propertiesen_US
dc.subjectAntioxidant activityen_US
dc.subjectPhytochemical screeningen_US
dc.subjectSalvia verticillata extracten_US
dc.subjectTotal tannin quantificationen_US
dc.titleThe anti-candidal activity of salvia verticillata subsp. verticillata against several candida speciesen_US
dc.titleThe anti-candidal activity of salvia verticillata subsp. verticillata against several candida species
dc.typeArticleen_US

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