Evaluation of Antibody Levels and Certain Biochemical Parameters in the Patients Infected with SARS-COV-2

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dc.contributor.authorAktar, Gülseren Samancı
dc.contributor.authorMızraklı, Ayser
dc.contributor.authorDurak, Mehmet Hanifi
dc.contributor.authorOnur, Arzu Rahmanalı
dc.contributor.authorAslan, Özgür
dc.date.accessioned2024-04-24T19:13:18Z
dc.date.available2024-04-24T19:13:18Z
dc.date.issued2022
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: In cases with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease clinical usefulness of serological tests remains uncertain. The study aimed to evaluate anti-SARS- CoV-2 antibody and some biochemical parameters such as leukocyte (WBC), neutrophil (NEU), lymphocyte (LYM), thrombocyte (PLT), erythrocyte (RBC), hemoglobin (Hb), ferritin, procalcitonin (PCT), C-reactive protein (CRP) and D-dimer in the patient specimens sent from the polyclinic and service/intensive care unit. Materials and Methods: A total of 110 patients’ specimens sent from the polyclinic and from the service/intensive care unit were used. SARS-CoV-2 RT PCR, immunoassay SARS-CoV-2 antibody and other biochemical tests were assessed. Results: Anti-SARS-CoV-2 antibody was positive in 11 (5 polyclinic, 6 service/intensive care) of 24 patients with negative RT-PCR test. Significant difference was determined between the two groups from the polyclinic and service/intensive care unit in terms of WBC, NEU, RBC and Hb, ferritin, CRP, PCT and D-dimer levels (p= 0.001, 0.007, 0.002, 0.006, 0.001, <0.001, 0.012 and 0.001, respectively), whereas other parameters (lymphocyte, platelet) showed no significant difference. Conclusions: Because of gradually increasing rate of exposure to SARS-CoV-2, we suggest that seroprevalence needs to be determined, antibody levels should be identified before vaccination, and antibody should be studied in the symptomatic patients with negative RT-PCR.en_US
dc.identifier.endpage24en_US
dc.identifier.issn1308-9315
dc.identifier.issn2148-8797
dc.identifier.issue1en_US
dc.identifier.startpage19en_US
dc.identifier.trdizinid523840
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/523840
dc.identifier.urihttps://hdl.handle.net/11468/28524
dc.identifier.volume36en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofFırat Üniversitesi Sağlık Bilimleri Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of Antibody Levels and Certain Biochemical Parameters in the Patients Infected with SARS-COV-2en_US
dc.titleEvaluation of Antibody Levels and Certain Biochemical Parameters in the Patients Infected with SARS-COV-2
dc.typeArticleen_US

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