Adenosine deaminase activity in diagnosis of tuberculous ascites
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Tarih
1997
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Between April 1993-September 1995, we studied the activity of adenosine deaminase (ADA) in the peritoneal fluid of 72 patients who were divided into three groups according to causes of ascites, as follows: tuberculous peritonitis (group I), secondary to malignant tumors (group II), cirrhosis of the liver (group III). In tuberculous ascitic fluid, ADA levels were 55.4±7.3 IU/L (mean±SD), which was significantly more than that noted in cirrhotic (7.6±3.9 IU/L), or malignant (15.5±7.7 IU/L) ascitic fluids (P<0.001, for each). At a cutt-off value of greater than 30IU/L, the sensitivity, specificity, positive and negative predictive values were 95.7%, 100%, 92.5% and 100%, respectively. These findings suggest that the ascitic fluid ADA activity may be used to identify patients in whom the diagnosis of abdominal tuberculosis must be pursued.
Açıklama
Anahtar Kelimeler
Kaynak
Turkish Journal of Medical Sciences
WoS Q Değeri
Scopus Q Değeri
Cilt
27
Sayı
3
