Determination of BMP-15, BMPR-1B and GDF-9 Gene Mutations of the Indigenous Sheep Breeds in Turkey

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dc.contributor.authorGursel, Feraye Esen
dc.contributor.authorAkis, Iraz
dc.contributor.authorDurak, Hanefi
dc.contributor.authorMengi, Ahmet
dc.contributor.authorOztabak, Kemal
dc.date.accessioned2024-04-24T17:47:41Z
dc.date.available2024-04-24T17:47:41Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe high ovulation rate and fertility are very important production traits in sheep production. The aim of the study was to determine the BMP-15, BMPR-1B and GDF-9 gene mutations which are related with the high ovulation with high ovulation rate in Chios, Kivircik, Awassi and Imrose sheep breeds. Fifty sheep from each breed were provided for this study. Blood samples for all the animals were collected in sterile-2 ml tubes containing EDTA. Genomic DNAs were isolated using a standard salt-out method. Thereafter target sites were amplified with polymerase chain reaction (PCR). FecX(I), FecX(H), FecX(G), FecX(B) mutations in BMP-15 gene, FecB mutation in BMPR-IB gene and FecG(H) mutation in GDF-9 gene were determined by restriction fragment length polymorphism (RFLP) method. All individuals were non-carriers for these mutations, except FecXG mutation in BMP-15 gene. The animals analyzed in this study were found to be heterozygous carriers for FecXG mutation. There may be other genes affecting fertility in Anatolian breeds. For the genetically explanation of multiple lambing, especially in Chios sheep, it was concluded that different genes should be investigated in the further studies.en_US
dc.description.sponsorshipResearch Support Unit of Istanbul University [2432]en_US
dc.description.sponsorshipThis study is supported by The Research Support Unit of Istanbul University as the Project number 2432en_US
dc.identifier.endpage729en_US
dc.identifier.issn1300-6045
dc.identifier.issue5en_US
dc.identifier.startpage725en_US
dc.identifier.urihttps://hdl.handle.net/11468/22683
dc.identifier.volume17en_US
dc.identifier.wosWOS:000295359100007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBmp-15en_US
dc.subjectBmpr-1ben_US
dc.subjectGdf-9en_US
dc.subjectMutationen_US
dc.titleDetermination of BMP-15, BMPR-1B and GDF-9 Gene Mutations of the Indigenous Sheep Breeds in Turkeyen_US
dc.titleDetermination of BMP-15, BMPR-1B and GDF-9 Gene Mutations of the Indigenous Sheep Breeds in Turkey
dc.typeArticleen_US

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