Mortality Associated with Surgical Site Infections Following Cardiac Surgery: Insights from the International ID-IRI Study

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dc.contributor.authorErdem, Hakan
dc.contributor.authorAnkarali, Handan
dc.contributor.authorAl-Tawfiq, Jaffar A.
dc.contributor.authorAngamuthu, Kumar
dc.contributor.authorPiljic, Dragan
dc.contributor.authorUmihanic, Ajdin
dc.contributor.authorDayyab, Farouq
dc.date.accessioned2025-02-22T14:10:54Z
dc.date.available2025-02-22T14:10:54Z
dc.date.issued2025
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives: Surgical site infections (SSIs) after cardiac surgery increase morbidity and mortality rates. This multicenter study aimed to identify mortality risk factors associated with SSIs after heart surgery. Methods: Conducted from January to March 2023, this prospective study included 167 patients aged >16 years with post-heart surgery SSIs. The primary focus was the 30-day mortality. Univariate analysis and multivariate logistic regression utilizing the backward elimination method were used to establish the final model. Results: Several factors significantly correlated with mortality. These included urinary catheterization (odds ratio [OR] 14.197; 90% confidence interval [CI] 12.198-91.721]), emergent surgery (OR 8.470 [90% CI 2.028-35.379]), valvular replacement (OR 4.487 [90% CI 1.001-20.627]), higher quick Sequential Organ Failure Assessment scores (OR 3.147 [90% CI 1.450-6.827]), advanced age (OR 1.075 [90% CI 1.020-1.132]), and postoperative re-interventions within 30 days after SSI (OR 14.832 [90% CI 2.684-81.972]). No pathogens were isolated from the wound cultures of 53 (31.7%) patients. A total of 43.1% of SSIs (n = 72) were due to gram-positive microorganisms, whereas 27.5% of cases (n = 46) involved gram-negatives. Among the gram-positive bacteria, Staphylococci (n = 30, 17.9%) were the predominant microorganisms, whereas Klebsiella (n = 16, 9.6%), Escherichia coli (n = 9, 5.4%), and Pseudomonas aeruginosa (n = 7, 4.2%) were the most prevalent. Conclusions: To mitigate mortality after heart surgery, stringent infection control measures and effective surgical antisepsis are crucial, particularly, in the elderly. The clinical progression of the disease is reflected by the quick Sequential Organ Failure Assessment score and patient re-intervention, and effective treatment is another essential component of SSI management. © 2025 The Authorsen_US
dc.identifier.doi10.1016/j.ijregi.2025.100566
dc.identifier.issn2772-7076
dc.identifier.scopus2-s2.0-85215974104en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijregi.2025.100566
dc.identifier.urihttps://hdl.handle.net/11468/29864
dc.identifier.volume14en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherElsevier Ltden_US
dc.relation.ispartofIJID Regionsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_Scopus_20250222
dc.subjectCABGen_US
dc.subjectCardiacen_US
dc.subjectInfectionen_US
dc.subjectMortalityen_US
dc.subjectSurgicalen_US
dc.titleMortality Associated with Surgical Site Infections Following Cardiac Surgery: Insights from the International ID-IRI Studyen_US
dc.typeArticleen_US

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