Yenidoğan yoğun bakım ünitesinde mekonyum aspirasyon sendromlu yenidoğanların değerlendirilmesi
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Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Yüzüncü Yıl Üniversitesi Tıp Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Mekonyum aspirasyon sendromu (MAS) term infantlarda solunum sıkıntısı nedenlerinden olup
değişken morbidite ve mortalite ile seyredebilmektedir. Bu çalışmanın amacı MAS tanısı konan
yenidoğanlarda demografik verileri, muhtemel risk faktörlerini ayrıca morbidite ve mortalite ile ilgili
durumları değerlendirmektir.
Gereç ve Yöntem: Bu çalışmamızda Dicle Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Yenidoğan
Yoğun Bakım Ünitesi’nde (YYBÜ) Ocak 2011- Eylül 2013 tarihleri arasında MAS tanısı alan 106 yenidoğan
retrospektif olarak değerlendirildi.
Bulgular: MAS YYBÜ yatışlarının %1.05’inden sorumlu bulundu. Olgularımızın 51’i (%48.1) erkek, 55’i
(%51.9) kız, 63’ü (%59.4) term, 25’i (%23.6) post-term idi. Gestasyon haftaları 38.6 ± 2.4 (34-43) hafta,
doğum ağırlıkları 3136 ± 655 (1700-4300) gr bulundu. Ortalama yatış süreleri 8.7 ± 4.4 (3-27) gündü. 54 (%
50.9) olgunun 1. dakika Apgar skoru ≤ 3 ve 10 (%9.43) olgunun 5. dakika Apgar skoru ≤ 3 idi. Mortalite
oranı %21.7 idi.
Sonuç: 1. dakika Apgar skoru ≤ 3 olması MAS’lı olgularda artmış morbidite ve mortalite ile ilişkili olarak
bulundu. MAS ile ilişkili risk faktörlerinin tanımlanması hastalığın teşhisinde ve erken tedavi stratejilerinin
geliştirilmesinde önemlidir. Post-term gebeliklerden korunmakla ve fetal distres durumunda sezeryan
doğumların uygun zamanda yapılması ile morbidite ve mortalite oranlarının iyileştirilmesinin mümkün
olacağı düşünüldü.
Aim: Meconium aspiration syndrome (MAS) is one of the common causes of respiratory distress in term infants presenting highly variable morbidity and mortality. The aim of this study was to evaluate the demographic data, possible risk factors, factors associated with morbidity and mortality in MAS newborns. Materials and Methods: The study was conducted at Neonatal Intensive Care Unit (NICU) of Dicle University Medical School Department of Pediatrics. A total of 106 newborns diagnosed as MAS between January 2011 and September 2013 were retrospectively evaluated. Results: MAS found to be responsible from 1.05% of NICU admissions. The study included 51 (48.1%) male and 55 (51.9%) female newborns. Of them 63 (59.4%) were term infants and 25 (23.6%) were postterm. The mean gestational age was 38.6 ± 2.4 (34- 43) weeks and the mean birth weight was 3136 ± 655 (1700-4300) gram. The mean hospitalization duration was 8.7±4.4 (range 3-27) days. The first minute APGAR score ≤ 3 was found in 54 (50.9%) and the fifth minute APGAR score ≤ 3 was found in 10 (9.43%) of newborns with MAS. The overall mortality was 21.7%. Conclusion: The first minute APGAR score ≤ 3 was found to be related to increased morbidity and mortality. Determination of risk factors associated with MAS is important regarding diagnosis and implementing early treatment strategies. It was tought that morbidity and mortality rates could be ameliorated by prevention of post term gestation and performing cesarian section at appropriate time.
Aim: Meconium aspiration syndrome (MAS) is one of the common causes of respiratory distress in term infants presenting highly variable morbidity and mortality. The aim of this study was to evaluate the demographic data, possible risk factors, factors associated with morbidity and mortality in MAS newborns. Materials and Methods: The study was conducted at Neonatal Intensive Care Unit (NICU) of Dicle University Medical School Department of Pediatrics. A total of 106 newborns diagnosed as MAS between January 2011 and September 2013 were retrospectively evaluated. Results: MAS found to be responsible from 1.05% of NICU admissions. The study included 51 (48.1%) male and 55 (51.9%) female newborns. Of them 63 (59.4%) were term infants and 25 (23.6%) were postterm. The mean gestational age was 38.6 ± 2.4 (34- 43) weeks and the mean birth weight was 3136 ± 655 (1700-4300) gram. The mean hospitalization duration was 8.7±4.4 (range 3-27) days. The first minute APGAR score ≤ 3 was found in 54 (50.9%) and the fifth minute APGAR score ≤ 3 was found in 10 (9.43%) of newborns with MAS. The overall mortality was 21.7%. Conclusion: The first minute APGAR score ≤ 3 was found to be related to increased morbidity and mortality. Determination of risk factors associated with MAS is important regarding diagnosis and implementing early treatment strategies. It was tought that morbidity and mortality rates could be ameliorated by prevention of post term gestation and performing cesarian section at appropriate time.
Açıklama
Anahtar Kelimeler
Mekonyum aspirasyon sendromu, Yenidoğan, Risk faktörleri, Mortalite, Meconium aspiration syndrome, Newborn, Risk factors, Mortality
Kaynak
Van Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
21
Sayı
4
Künye
Şen, V., Karabel, M., Uluca, Ü., Ağaçayak, E., Tan, İ., Karabel, D. ve diğerleri. (2014). Yenidoğan yoğun bakım ünitesinde mekonyum aspirasyon sendromlu yenidoğanların değerlendirilmesi. Van Tıp Dergisi, 21(4), 230-235.
