Investigating the Pharmacological Potential of Micromeria myrtifolia Boiss. & Hohen.: Phenolic Profiling and Biological Activity Assessments

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dc.contributor.authorErsoy, Ezgi
dc.contributor.authorBatal Yildizhan, Rumeysa
dc.contributor.authorYilmaz, Mustafa Abdullah
dc.contributor.authorYeşil Cantürk, Yeter
dc.contributor.authorŞahin, Hasan
dc.contributor.authorEroğlu Özkan, Esra
dc.contributor.authorBoğa, Mehmet
dc.date.accessioned2025-02-22T14:10:56Z
dc.date.available2025-02-22T14:10:56Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractMicromeria myrtifolia Boiss. & Hohen. is a valuable medicinal plant in Türkiye, recognized for its extensive applications across the country. In this study, plant samples were collected from Muğla, Türkiye and extracts from both the aerial parts and roots were prepared using ethanol. To elucidate their phytochemical composition, a comprehensive LC-MS/MS analysis was conducted. The results revealed that both extracts were quite rich in phenolic compounds. Notably, nicotiflorin was the major constituent in both extracts (12878.31±355.44 μg/g extract in the aerial parts and 47512.4±1311.34 μg/g extract in the roots) along with significant phenolic acids such as rosmarinic acid and caffeic acid as well as flavonoids like hesperidin. Moreover, both extracts demonstrated substantial antioxidant activities compared to the synthetic antioxidant compounds as evaluated by DPPH free radical scavenging, ABTS cation radical scavenging, and CUPRAC activity assays. Both aerial parts and root extracts also exhibited meaningful anti-glucosidase activity with 73.03±0.16% and 47.06±0.41%, respectively, at 2 mg/mL concentration. The root extract also showed moderate butyrylcholinesterase inhibitory activity. This study contributes to the existing body of knowledge with valuable insights regarding the phytochemical profile and biological activities of M. myrtifolia, paving the way for future research aimed at exploring its medicinal properties and potential uses in traditional and modern medicine. © 2024, ABADER (Adıyaman Bilimsel Arastırmalar Dernegi). All rights reserved.en_US
dc.identifier.doi10.31594/commagene.1576852
dc.identifier.endpage114en_US
dc.identifier.issn2602-456X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85214407483en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage103en_US
dc.identifier.urihttps://doi.org/10.31594/commagene.1576852
dc.identifier.urihttps://hdl.handle.net/11468/29902
dc.identifier.volume8en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherABADER (Adıyaman Bilimsel Arastırmalar Dernegi)en_US
dc.relation.ispartofCommagene Journal of Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_Scopus_20250222
dc.subjectantioxidanten_US
dc.subjectenzyme inhibitionen_US
dc.subjectLC-MS/MSen_US
dc.subjectMicromeria Benthen_US
dc.titleInvestigating the Pharmacological Potential of Micromeria myrtifolia Boiss. & Hohen.: Phenolic Profiling and Biological Activity Assessmentsen_US
dc.title.alternativeMicromeria myrtifolia Boiss. & Hohen. Bitkisinin Farmakolojik Potansiyelinin Araştırılması: Fenolik İçeriğinin ve Biyolojik Aktivitelerinin Belirlenmesien_US
dc.typeArticleen_US

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