USAGE OF CONDUITS IN PERIPHERAL NERVE REPAIRMENT, CURRENT AND ESSENTIAL MANAGEMENTS: REVIEW OF THE LITERATURE

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dc.contributor.authorBozkurt, Mehmet
dc.contributor.authorKapi, Emin
dc.contributor.authorKulahci, Yalcin
dc.date.accessioned2024-04-24T17:47:34Z
dc.date.available2024-04-24T17:47:34Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractPeripheral nerve injury is an important cause of patient morbidity today and these injuries continue to be among the most challenging problems faced by surgeons. Important advances in microsurgery, understanding of the details of the biology and chemistry of nerve cell culture, genetic techniques, provides optimism for the improved surgical treatment of peripheral nerve injuries. Primary interfascicular neuroraphy is the most desirable approach for peripheral nerve injuries. If the defects has been, for those defects with significant gaps precluding primary repair, nerve autografting with microsurgical technique is considered standart care. Autografting, however, can be limited due to donor site morbidity. In this respect, included are investigations utilizing different and alternative biologic active materials ant the few clinical applications of the blood vessel, muscle tissue and tubularized membrane. One possible alternative to autogenous tissue replacement is the development of engineered constructs to replace those elements necessary for nerve regeneration, including a scaffold, support cells, induction factors and extracellular matrices. Despite advances in the field of tissue engineering, results to date with nerve conduits have failed to equal the nerve regeneration achieved with autogenous grafts for large distances. Scaffolds is a key element and it is useful as it promotes axonal elongation and it was implanted for intraluminal field of conduits. Many growth factors was described for affecting in the regeneration phase for nerve regeneration. Modification of matrices was building for used are pharmacologic or exogen agents. Additional development of the nerve conduit may lead to further improvements in outcome.en_US
dc.identifier.endpage83en_US
dc.identifier.issn2528-8644
dc.identifier.issue2en_US
dc.identifier.startpage74en_US
dc.identifier.urihttps://hdl.handle.net/11468/22610
dc.identifier.volume17en_US
dc.identifier.wosWOS:000416764400005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotren_US
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofTurkish Journal of Plastic Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRepair Of Peripheral Nervesen_US
dc.subjectConduiten_US
dc.subjectScaffolden_US
dc.subjectTissue Engineeringen_US
dc.titleUSAGE OF CONDUITS IN PERIPHERAL NERVE REPAIRMENT, CURRENT AND ESSENTIAL MANAGEMENTS: REVIEW OF THE LITERATUREen_US
dc.titleUSAGE OF CONDUITS IN PERIPHERAL NERVE REPAIRMENT, CURRENT AND ESSENTIAL MANAGEMENTS: REVIEW OF THE LITERATURE
dc.typeReview Articleen_US

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