Effect of a 50-Hz Sinusoidal Electromagnetic Field on the Integrity of Experimental Colonic Anastomoses Covered with Fibrin Glue

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dc.contributor.authorGirgin, Sadullah
dc.contributor.authorOzturk, Hayrettin
dc.contributor.authorGedik, Ercan
dc.contributor.authorAkpolat, Veysi
dc.contributor.authorKale, Ebru
dc.contributor.authorOzturk, Hulya
dc.date.accessioned2024-04-24T17:47:57Z
dc.date.available2024-04-24T17:47:57Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground. Low-frequency magnetic fields have been shown to affect biological processes. In this article the effects of 50-Hz sinusoidal magnetic field (MF) stimulation and application of fibrin glue on the healing of experimental colonic anastomoses were investigated. Material and Methods. Twenty-eight rats were divided into four groups. Group 1 underwent 2-cm left colonic resection and primary anastomosis. Group 2 underwent normal resection anastomosis and the area was covered with fibrin glue. Group 3 underwent normal resection anastomosis and the rats were exposed to a 50-Hz sinusoidal MF. Group 4 underwent normal resection anastomosis, the anastomosis area was covered with fibrin glue, and the rats were exposed to a 50-Hz sinusoidal MF. Investigations included bursting pressure measurement, hydroxyproline content, and histopathological changes. Results. Tissue hydroxyproline levels and anastomotic bursting pressures of groups 2, 3, and 4 were significantly higher than in group 1. Collagen deposition and fibroblast infiltration in groups 2, 3, and 4 had higher scores than in group 1. Furthermore, these results were significantly higher in group 4 rats than in the other groups. Histopathological examination of the anastomosis revealed significantly better healing patterns for group 4 than for groups 1, 2, and 3. Conclusions. A50-Hz sinusoidal MF stimulation and application of fibrin glue provided a significant gain in anastomotic healing in the large intestine. A combination of a 50-Hz sinusoidal MF and fibrin glue has significantly favorable effects on healing of experimental colon anastomosis (Adv Clin Exp Med 2009, 18, 1, 13-18).en_US
dc.identifier.endpage18en_US
dc.identifier.issn1899-5276
dc.identifier.issn2451-2680
dc.identifier.issue1en_US
dc.identifier.startpage13en_US
dc.identifier.urihttps://hdl.handle.net/11468/22822
dc.identifier.volume18en_US
dc.identifier.wosWOS:000270038600002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherWroclaw Medical Univen_US
dc.relation.ispartofAdvances in Clinical and Experimental Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectColonic Anastomosisen_US
dc.subject50-Hz Sinusoidal Magnetic Fielden_US
dc.subjectFibrin Glueen_US
dc.titleEffect of a 50-Hz Sinusoidal Electromagnetic Field on the Integrity of Experimental Colonic Anastomoses Covered with Fibrin Glueen_US
dc.titleEffect of a 50-Hz Sinusoidal Electromagnetic Field on the Integrity of Experimental Colonic Anastomoses Covered with Fibrin Glue
dc.typeArticleen_US

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