Monocyte count / HDL cholesterol ratio: A new marker in diabetic retinopathy

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dc.authorid0000-0002-6624-8063en_US
dc.authorid0000-0002-3591-721Xen_US
dc.contributor.authorSolmaz, İhsan
dc.contributor.authorKarahan, Mine
dc.date.accessioned2023-09-25T12:40:42Z
dc.date.available2023-09-25T12:40:42Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractAim: Diabetic retinopathy (DRP) makes up a significant portion of visual impairments. DRP is divided into proliferative and nonproliferative forms. Monocytes contribute to inflammation, whereas HDL reinforces the reversal of inflammation through promoting anti-inflammatory pathways. The monocyte-to-HDL cholesterol ratio (MHR) is one of the indicators that have been included in recent inflammation studies. This study aims to investigate the diagnostic value of MHR and whether it can be utilized as an indicator of diabetic retinopathy. Materials and Methods: This study includes patients diagnosed at least 5 years ago with type II diabetes mellitus (DM) who are ≥ 18 years old and have an HbA1c value > 6.5. The control group is made up of patients aged ≥ 18 years that presented to the outpatient clinic for other ailments of the eye. The data were prospectively recorded through the hospital information system. The subjects were divided into 3 groups: proliferative retinopathy, non-proliferative retinopathy, and control. Results: The study included a total of 200 subjects: 70 patients with diabetic non-proliferative retinopathy, 87 patients with diabetic proliferative retinopathy, and 43 patients without retinopathy. There were 92 male (46%) and 108 female patients (54%). The mean age was 66.35 ± 11.3 years (19-96). In this prospective observational study, we found that the MHR values of experimental and control groups were significantly different (p = 0.046). The post hoc Tukey's honest significant difference (HSD) test revealed a statistically significant difference between the control and proliferative retinopathy groups (p = 0.040), but not the non-proliferative retinopathy group (p = 0.125). Conclusion: MHR has diagnostic potential for diabetic retinopathy, especially for the proliferative formen_US
dc.identifier.citationSolmaz, İ. ve Karahan, M. (2021). Monocyte count / HDL cholesterol ratio: A new marker in diabetic retinopathy. Annals of Medical Research, 28(2), 258-260.en_US
dc.identifier.doi10.5455/annalsmedres.2020.02.173en_US
dc.identifier.endpage260en_US
dc.identifier.issn2636-7688
dc.identifier.issue2en_US
dc.identifier.startpage258en_US
dc.identifier.trdizinid428686en_US
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/428686
dc.identifier.urihttps://hdl.handle.net/11468/12589
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/428686
dc.identifier.volume28en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorKarahan, Mine
dc.language.isoenen_US
dc.publisherİnönü Üniversitesi Tıp Fakültesien_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMonocyte-to-HDL ratioen_US
dc.subjectRetinopathyen_US
dc.subjectDiabetesen_US
dc.titleMonocyte count / HDL cholesterol ratio: A new marker in diabetic retinopathyen_US
dc.typeArticleen_US

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