The protective effect of vitamins E and C on the gastric mucosal barrier in rats irradiated with x-rays

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dc.contributor.authorKurt, Doğan
dc.contributor.authorKanay, Zeki
dc.contributor.authorSert, Cemil
dc.contributor.authorGüzel, Cihat
dc.date.accessioned2024-04-24T18:56:45Z
dc.date.available2024-04-24T18:56:45Z
dc.date.issued1999
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe protective effect of vitamins E and C on the gastric mucosal barrier in rats irradiated with X-rays was investigated. Thirty-two male Wistar Albino rats were used. The animals were divided into four groups and arranged of follows: the first group (n=8) was the sham group; the second group (n=8) was the control group which was irradiated with X-rays, the third group (n=8) to which vitamin C was administered and the fourth group (n=8) to which vitamin E was given. The animals in the groups except the sham group wereirradiated with 8.9 Gy X-rays. Twenty-four hours later, the animals were sacrificed by cervical disloca-tion. The stomach was removed and opened along the greater curvature. The amounts of mucus and phospholipid, which are the com-ponents of gastric mucosal barrier, were determined by Corne and Baur's method. The amounts in irriadiated rats were found to be lower relative to those in the rats which were not irradiated (p<0.001, p<0.001, respectively). The amounts were observed to be higher in the vitamin C administered group compared with the irradiated control group (p<0.001, 0<0.05, respectively). In the group to which vitamin E was given, the amounts were also found to be higher relative to those in the control group (p<0.001, p<0.05 respectively). The results indicate that vitamins E and C protect the gastric mucosal barrier against X-rays.en_US
dc.identifier.endpage554en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue5en_US
dc.identifier.startpage551en_US
dc.identifier.trdizinid9259
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/9259
dc.identifier.urihttps://hdl.handle.net/11468/25452
dc.identifier.volume29en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe protective effect of vitamins E and C on the gastric mucosal barrier in rats irradiated with x-raysen_US
dc.titleThe protective effect of vitamins E and C on the gastric mucosal barrier in rats irradiated with x-rays
dc.typeOtheren_US

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