Horizontal transmission of HBV among students in the Southeastern Anatolia
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Tarih
2000
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background/aim: In this study, the HBsAg Carrier State and horizontal transmission were investigated among primary and high school students in Diyarbakir, where HBsAg positivity is remarkably high. All results were compared with those of similar studies conducted previously in the same schools. Methods: Overall, 150 students from primary school first grade, 150 students from fifth grade, 200 students from eleventh grade and 200 adults were studied. In all cases HBsAg and anti-HBs were screened by ELISA. Results: HBsAg positivity was 2.7%, 6.1% and 6.2% in the first, fifth and eleventh grade students respectively, while anti-HBsAg positivity was 14%, 20% and 21% in these groups. In adults, HBsAg positivity was 10% and anti-HBsAg 49%. Our results were similar to those of a prior study performed in the same school eight years previously (p>0.05). When both the results from the present study and those from the previous one were evaluated, the difference between the first and fifth grade students was found to be significant (2.1% vs. 6.1% and p<0.05) but that between the fifth and eleventh grades was not (6.2%, p>0.05). This trend also applied to HBsAg positivity. Conclusion: It is concluded that in Diyarbakir and probably in Turkey generally the 7-11 year-old period seems to be the most critical age in the horizontal transmission of HBV infection. During high school years, this risk lessens. In addition to HBV vaccination at birth, it would therefore be appropriate to vaccinate first grade students at the age of seven for the next 7-8 years.
Açıklama
Anahtar Kelimeler
Anti-Hbs, Hbsag, Horizontal Transmission
Kaynak
Turkish Journal of Gastroenterology
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
11
Sayı
2
