Effects of active and passive smoking on antioxidant enzymes and antioxidant micronutrients

dc.contributor.authorYokuş, Beran
dc.contributor.authorMete, Nuriye
dc.contributor.authorÇakır, Ülker Dilek
dc.contributor.authorToprak, Gülten
dc.contributor.orcid0000-0003-4585-3712
dc.date.accessioned2024-04-24T17:56:19Z
dc.date.available2024-04-24T17:56:19Z
dc.date.issued2005
dc.departmentDicle Üniversitesi, Veteriner Fakültesi, Temel Bilimler Bölümü, Veterinerlik Biyokimyası Ana Bilim Dalıen_US
dc.description.abstractIn the present study, we analyzed the relationship between cigarette smoke exposure and several markers of oxidative status, plasma thiobarbituric acid reactive substances, erythrocyte glutathione peroxidase, superoxide dismutase and catalase in a group of students. Of the 105 men enrolled into the study, 35 had never smoked and not exposed to cigarette smoke at all. Thirty five had smoked at least 15 cigarettes per day for at least five years (active smokers) and 35 had been exposed to cigarette smoke at indoor environment at least 2 cigarette/day on ?5d/wk for > 6 months (passive smokers). The urine cotinine level was used as a smoking marker. Erythrocyte SOD activity and plasma TBARs were significantly higher in active and passive smokers than in non-smokers (p < 0.05). However, erythrocyte GSH-Px and CAT were significanly lower in active smokers than in non smokers (p < 0.05). Serum vitamin C and E levels were significantly lower in active and passive smokers than in nonsmokers (p < 0.05). For active and passive smokers, there were significant possitive correlations between urine cotinine levels and plasma TBARs levels (r = 0.60, p < 0.01, r = 0.43, p < 0.05) and a negative correlation between urine cotinine levels and plasma vitamin C (r = -0.48, p < 0.05, r = -0.59, p < 0.01). In conclusion, during both passive and active smoking, oxidative stress was clearly exacerbated and the dynamic balance between oxidation and antioxidation was seriously disrupted, which was closely related to many disorders or diseases in active and passive smokers.en_US
dc.identifier.citationYokuş, B., Mete, N., Çakır, Ü. D. ve Toprak, G. (2005). Effects of active and passive smoking on antioxidant enzymes and antioxidant micronutrients. Biotechnology and Biotechnological Equipment, 19(3), 117-123.
dc.identifier.doi10.1080/13102818.2005.10817238
dc.identifier.endpage123en_US
dc.identifier.issn1310-2818
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-26844464674
dc.identifier.scopusqualityQ3
dc.identifier.startpage117en_US
dc.identifier.urihttps://doi.org/10.1080/13102818.2005.10817238
dc.identifier.urihttps://hdl.handle.net/11468/23446
dc.identifier.urihttps://www.tandfonline.com/doi/abs/10.1080/13102818.2005.10817238
dc.identifier.volume19en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofBiotechnology and Biotechnological Equipment
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEffects of active and passive smoking on antioxidant enzymes and antioxidant micronutrientsen_US
dc.titleEffects of active and passive smoking on antioxidant enzymes and antioxidant micronutrients
dc.typeArticleen_US

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