The evaluation of nephropathy risk factors in type 2 diabetes

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dc.contributor.authorCelepkolu T.
dc.contributor.authorTanriverdi M.H.
dc.contributor.authorCelik S.B.
dc.contributor.authorBucaktepe P.G.E.
dc.contributor.authorCan H.
dc.contributor.authorAslan I.
dc.contributor.authorKibrisli E.
dc.date.accessioned2024-04-24T18:46:14Z
dc.date.available2024-04-24T18:46:14Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction: The prevalence of diabetes has been increasing at an alarming rate worldwide. Thus, the complications of diabetes are increasingly prevalent and each year three million people die as a result of its chronic complications. In our study, we aimed to compare nephropathic and non nephropathic patients according to socio-demographic features, biochemical parameters, and proteinuria characteristics. Methods: Data of 923 type 2 diabetic patients, who were admitted to our Department between January 2000 and December 2008, were analysed retrospectively. The records of 378 patients were included in the study and classified as normoalbuminuric, microalbuminuric and macroalbuminuric. These groups were compared in terms of demographic, clinical and laboratory findings to investigate the risk factors related to nephropathy. Results: Of the 378 patients, 224 were female (59%) and 154 were male (41%). The mean age was 58.9±9.7 years. A total of 100 patients (26.5%) with micro and macroalbuminuria were identified as nephropathic. In the nephropathic group, the levels of FBG (Fasting Blood Glucose), PBG (Postprandial Blood Glucose), HbA1c (Hemoglobin A1c=glycosylated hemoglobin), urea, and creatinine, and the duration of known diabetes were significantly increased when compared with the non-nephropathic group. Diastolic blood pressure and urea levels were significantly higher and creatinine clearance was significantly lower in the macroalbuminuric group. Conclusion: We found a significant relationship between nephropathy and HbA1c, an important indicator of blood glucose control. Therefore, it is essential to provide aggressive blood pressure management and long-term glycaemic control in order to reduce cardiovascular risk, prevent the development of diabetic nephropathy and ESRF (End Stage Renal Failure), and reduce overall mortality and morbidity. Education of diabetic patients about the risks and complications of elevated blood pressure and poor glycaemic control is a critical component of clinical practice.en_US
dc.identifier.endpage226en_US
dc.identifier.issn0393-6384
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84896872068
dc.identifier.scopusqualityN/A
dc.identifier.startpage221en_US
dc.identifier.urihttps://hdl.handle.net/11468/25118
dc.identifier.volume30en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherActa Medica Mediterraneaen_US
dc.relation.ispartofActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiabetesen_US
dc.subjectNephropathyen_US
dc.subjectRisk Factorsen_US
dc.titleThe evaluation of nephropathy risk factors in type 2 diabetesen_US
dc.titleThe evaluation of nephropathy risk factors in type 2 diabetes
dc.typeArticleen_US

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