Identification of free radicals formed in gamma-irradiated chlorpropamide and procainamide hydrochloride pharmaceutical raw materials by EPR spectroscopy

Basit Öğe Kaydı
dc.contributor.authorSütçü, Kerem
dc.contributor.authorOsmanoğlu, Yunus Emre
dc.date.accessioned2024-04-24T19:13:24Z
dc.date.available2024-04-24T19:13:24Z
dc.date.issued2023
dc.departmentDicle Üniversitesi, Ziya Gökalp Eğitim Fakültesi, Matematik ve Fen Bilimleri Eğitimi Bölümüen_US
dc.description.abstractIn this study, it was aimed to determine the structural properties of free radicals formed by gamma irradiation in chlorpropamide and procainamide hydrochloride drug raw materials, which are widely used in medicine, by using electron paramagnetic resonance spectroscopy. As a result of gamma irradiation, it was determined that two different radicals were formed in both chlorpropamide and procainamide hydrochloride samples. It was suggested that –N?H-, -NCH2?H2- and –N?H-, -N?HCH2- radicals were formed in chlorpropamide and procainamide hydrochloride samples, respectively. The simulated spectra closest to the experimental spectra recorded at room temperature of the samples studied in powder form were obtained using simulation software. The contributions of the proposed radicals to the experimental spectra were calculated. The g values of the obtained radicals and the hyperfine structure constants of the unpaired electrons were calculated.en_US
dc.identifier.citationSütçü, K., Osmanoğlu, Y. E. (2023). Identification of free radicals formed in gamma-irradiated chlorpropamide and procainamide hydrochloride pharmaceutical raw materials by EPR spectroscopy. Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 13(4), 2616-2621.
dc.identifier.doi10.21597/jist.1302560
dc.identifier.endpage2621en_US
dc.identifier.issn2146-0574
dc.identifier.issn2536-4618
dc.identifier.issue4en_US
dc.identifier.startpage2616en_US
dc.identifier.trdizinid1211226
dc.identifier.urihttps://doi.org/10.21597/jist.1302560
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1211226
dc.identifier.urihttps://hdl.handle.net/11468/28586
dc.identifier.volume13en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofIğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleIdentification of free radicals formed in gamma-irradiated chlorpropamide and procainamide hydrochloride pharmaceutical raw materials by EPR spectroscopyen_US
dc.titleIdentification of free radicals formed in gamma-irradiated chlorpropamide and procainamide hydrochloride pharmaceutical raw materials by EPR spectroscopy
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Identification of Free Radicals Formed in Gamma-Irradiated Chlorpropamide and Procainamide Hydrochloride Pharmaceutical Raw Materials by EPR Spectroscopy.pdf
Boyut:
329.14 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu