Plasma homocysteine levels in patients with acute ischemic stroke: A cross-sectional study

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dc.contributor.authorSönmezler A.
dc.contributor.authorUlaş T.
dc.contributor.authorDal M.S.
dc.contributor.authorDemir M.E.
dc.contributor.authorKarababa I.F.
dc.contributor.authorBüyükhatipo?lu H.
dc.date.accessioned2024-04-24T17:58:24Z
dc.date.available2024-04-24T17:58:24Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: In this study, we aimed to investigate plasma homocysteine (Hcy) changes in patients within the acute period of ischemic stroke. Material and Methods: In this cross-sectional study, a total of 110 patients with acute ischemic stroke presenting within 48 hours of onset and 45 age and gender-matched healthy subjects were evaluated. Hcy was measured on 2nd, 4th, 7th, 10th and 14th days of the hospitalization. Control samples were also collected after a 12-hour fasting period. Results: Statistically significantly lower Hcy levels were found in acute ischemic stroke patients on the 2nd day compared to the control group (p<0.001). No significant difference was found in the 4th day between the groups (p=0.478). In all other days on which test was performed, Hcy levels were statistically significantly higher in acute ischemic stroke group compared to the control group (p<0.001 for all). Conclusion: This study suggests that Hcy levels are not significantly elevated after recent ischemic stroke, but rise in the 2nd week of admission, and our findings do not support the hypothesis that raised plasma Hcy levels predate ischemic stroke. Therefore, increased plasma Hcy level is a consequence of disease process, and has no value as a predictor of ischemic stroke. © 2013 by Türkiye Klinikleri.en_US
dc.identifier.doi10.5336/medsci.2012-29486
dc.identifier.endpage388en_US
dc.identifier.issn1300-0292
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84874614913
dc.identifier.scopusqualityQ4
dc.identifier.startpage384en_US
dc.identifier.urihttps://doi.org/10.5336/medsci.2012-29486
dc.identifier.urihttps://hdl.handle.net/11468/23898
dc.identifier.volume33en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherTurkiye Kliniklerien_US
dc.relation.ispartofTurkiye Klinikleri Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHomocysteineen_US
dc.subjectRisk Factorsen_US
dc.subjectStrokeen_US
dc.titlePlasma homocysteine levels in patients with acute ischemic stroke: A cross-sectional studyen_US
dc.titlePlasma homocysteine levels in patients with acute ischemic stroke: A cross-sectional study
dc.title.alternativeAkut i?skemik i?nmeli hastalarda plazma homosistein seviyeleri: Kesitsel bir çalışmaen_US
dc.title.alternativeAkut i?skemik i?nmeli hastalarda plazma homosistein seviyeleri: Kesitsel bir çalışma
dc.typeArticleen_US

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