Effects of cypermethrin on serum biochemistry and liver histopathology of anabas testudineus

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dc.contributor.authorVelmurugan, Babu
dc.contributor.authorSatar, Elif İpek
dc.contributor.authorYolcu, Murat
dc.contributor.authorUysal, Ersin
dc.date.accessioned2024-04-24T17:58:12Z
dc.date.available2024-04-24T17:58:12Z
dc.date.issued2024
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractCypermethrin is one of the most commonly used pesticides. In this study, the effects of cypermethrin on serum biochemistry and liver histology of Anabas testudineus were investigated. The fish have been exposed to sub-lethal concentrations of cypermethrin for the 7th, 14th, and 21st days and one control was considered. AST, ALT, and ALP showed concentration-and days-dependent increases in all experimental groups. Bilirubin levels increased significantly (p<0.05) in cypermethrin groups. No statistically significant difference in bilirubin levels was observed between the concentrations of 0.015 and 0.030 mg L-1 on days 7th and 14th. Protein levels decreased in response to cypermethrin on all days when compared to controls. Statistically significant differences in protein levels weren’t observed between all concentrations on days 7th and 14th and between concentrations of 0.015 and 0.030 mg L-1 on days 21st. Light microscopy revealed hepatocyte hypertrophy, sinusoidal dilation, granular degeneration, congestion, pycnosis, and focal necrosis in the liver. AST ALT, ALP, bilirubin, protein levels, and histopathology can be used as possible markers for biological monitoring and chemical risk assessment in aquatic organisms. © 2024, Islamic Azad University. All rights reserved.en_US
dc.description.sponsorshipJawaharlal Nehru Memorial Fund, JNMFen_US
dc.description.sponsorshipThis study was supported by the Jawaharlal Nehruen_US
dc.description.sponsorshipThis study was supported by the Jawaharlal Nehru Memorial Fund (JNMF).en_US
dc.identifier.citationVelmurugan, B., Satar, E. İ., Yolcu, M. ve Uysal, E. (2024). Effects of cypermethrin on serum biochemistry and liver histopathology of anabas testudineus. Journal of Chemical Health Risks, 14(1), 167-174.
dc.identifier.doi10.22034/jchr.2023.1948154.1479
dc.identifier.endpage174en_US
dc.identifier.issn2251-6719
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85187180518
dc.identifier.scopusqualityQ3
dc.identifier.startpage167en_US
dc.identifier.urihttps://doi.org/10.22034/jchr.2023.1948154.1479
dc.identifier.urihttps://hdl.handle.net/11468/23699
dc.identifier.volume14en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherIslamic Azad Universityen_US
dc.relation.ispartofJournal of Chemical Health Risks
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiochemical parametersen_US
dc.subjectHistopathologyen_US
dc.subjectLiveren_US
dc.subjectPesticideen_US
dc.titleEffects of cypermethrin on serum biochemistry and liver histopathology of anabas testudineusen_US
dc.titleEffects of cypermethrin on serum biochemistry and liver histopathology of anabas testudineus
dc.typeArticleen_US

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