Effect of a 50-Hz sinusoidal electromagnetic field on the integrity of experimental colonic anastomoses covered with fibrin glue

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dc.contributor.authorGirgin S.
dc.contributor.authorOzturk H.
dc.contributor.authorGedik E.
dc.contributor.authorAkpolat V.
dc.contributor.authorKale E.
dc.contributor.authorOzturk H.
dc.date.accessioned2024-04-24T18:45:38Z
dc.date.available2024-04-24T18:45:38Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground. Low-frequency magnetic fields have been shown to affect biological In this article the effects of 50-Hz sinusoidal magnetic field (MF) stimulation and application of fibrin glue on the healing of experimental colonic anastomoses were investigated. Material and Methods. Twenty-eight rats were divided into four groups. Group 1 underwent 2-cm left colonic resection and primary anastomosis. Group 2 underwent normal resection anastomosis and the area was covered with fibrin glue. Group 3 underwent normal resection anastomosis and the rats were exposed to a 50-Hz sinusoidal MF. Group 4 underwent normal resection anastomosis, the anastomosis area was covered with fibrin glue, and the rats were exposed to a 50-Hz sinusoidal MF. Investigations included bursting pressure measurement, hydroxypro-line content, and histopathological changes. Results. Tissue hydroxyproline levels and anastomotic bursting pressures of groups 2, 3, and 4 were significantly higher than in group 1. Collagen deposition and fibroblast infiltration in groups 2, 3, and 4 had higher scores than in group 1. Furthermore, these results were significantly higher in group 4 rats than in the other groups. Histopathological examination of the anastomosis revealed significantly better healing patterns for group 4 than for groups 1, 2, and 3. Conclusions. A 50-Hz sinusoidal MF stimulation and application of fibrin glue provided a significant gain in anastomotic healing in the large intestine. A combination of a 50-Hz sinusoidal MF and fibrin glue has significantly favorable effects on healing of experimental colon anastomosis. © Copyright by Wroclaw Medical University.en_US
dc.identifier.endpage18en_US
dc.identifier.issn1230-025X
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-64249112625
dc.identifier.scopusqualityQ1
dc.identifier.startpage13en_US
dc.identifier.urihttps://hdl.handle.net/11468/24722
dc.identifier.volume18en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofAdvances in Clinical and Experimental Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject50-Hz Sinusoidal Magnetic Fielden_US
dc.subjectColonic Anastomosisen_US
dc.subjectFibrin Glueen_US
dc.titleEffect of a 50-Hz sinusoidal electromagnetic field on the integrity of experimental colonic anastomoses covered with fibrin glueen_US
dc.titleEffect of a 50-Hz sinusoidal electromagnetic field on the integrity of experimental colonic anastomoses covered with fibrin glue
dc.typeArticleen_US

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