The effects of magnesium sulphate and alfentanil combination on haemodynamic control in general anaesthesia

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dc.contributor.authorTurhanoglu S.
dc.contributor.authorOzyilmaz M.A.
dc.contributor.authorCinar F.S.
dc.contributor.authorTok D.
dc.contributor.authorOlmez G.
dc.contributor.authorBayhan N.
dc.date.accessioned2024-04-24T17:58:49Z
dc.date.available2024-04-24T17:58:49Z
dc.date.issued1999
dc.departmentDicle Üniversitesien_US
dc.description.abstractSixty ASA class I or II patients were included to the study in which the effects of magnesium sulphate and alfentanil combination on the haemodynamic response to tracheal intubation and intraoperative haemodynamic control had been investigated. The patients were randomly allocated into three groups. At the induction of anaesthesia, the patients of group I (n=20) were received isotonic sodium chloride IV bolus and infusion, and 10 ?g/kg alfentanil, group II (n=20) were received IV magnesium sulphate 20 mg/kg bolus and 10 mg/kg/h infusion, and group III (n=20) were received IV magnesium sulphate 20 mg/kg bolus with 10 mg/kg/h infusion and 10 ?g/kg alfentanil. Anaesthesia induction and maintenance were performed respectively with thiopentone 5 mg/kg, isoflurane (% 1-1,5) in 50 % nitrous oxide and 50 % oxygen in all groups. Magnesium and alfentanil combination produced better control of arterial pressure and heart rate than magnesium and alfentanil alone (p<0.05). Furthermore, the consumption of alfentanil during the surgery were found significantly higher in group I than groups II and III (p<0.05). In conclusion we considered that the doses of magnesium sulphate and alfentanil combination in this study were adequate to attenuate the haemodynamic response to tracheal intubation and produce better control of arterial pressure and heart rate.en_US
dc.identifier.endpage507en_US
dc.identifier.issn1016-5150
dc.identifier.issue9en_US
dc.identifier.scopus2-s2.0-0033377063en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage503en_US
dc.identifier.urihttps://hdl.handle.net/11468/24118
dc.identifier.volume27en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlfentanilen_US
dc.subjectHaemodynamic Response To Tracheal İntubationen_US
dc.subjectIntraoperative Control Of Haemodynamicsen_US
dc.subjectMagnesium Sulphateen_US
dc.titleThe effects of magnesium sulphate and alfentanil combination on haemodynamic control in general anaesthesiaen_US
dc.title.alternativeGenel anestezide magnezyum sulfat ve alfentanil'in birlikte kullaniminin hemodinami uzerine etkilerien_US
dc.typeArticleen_US

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