Effect of exercise on blood antioxidant status and erythrocyte lipid peroxidation: Role of dietary supplementation of vitamin E

Basit Öğe Kaydı
dc.contributor.authorAtmaca, Mukadder
dc.contributor.authorKelle, Mustafa
dc.contributor.authorDiken, Hüda
dc.contributor.authorŞermet, Abdurrahman
dc.contributor.authorTümer, Cemil
dc.date.accessioned2024-04-24T18:56:45Z
dc.date.available2024-04-24T18:56:45Z
dc.date.issued1999
dc.departmentDicle Üniversitesien_US
dc.description.abstractWe tested the effects of moderate physical exercise on the blood antioxidant capacity and erythrocyte lipid peroxidation in 21 Wistar albino rats. Erythrocyte superoxide dismutase (SOD) activity increased significantly (p<0.05) in control exercised animals (C-Ex), but catalase activity did not change. SOD activity was decreased by dietary supplementation of vitamin E (p<0.05). In vitamin E supplemented group (E-Ex), catalase activity was reduced in comparision to C-Ex group. Total glutathione (total GSH) level was unaffected by the exercise. However, significant reduction was observed in reduced glutathione (GSH), whereas oxidized glutathione (GSSG) increased (p<0.01 and p<0.001, respectively). In E-Ex animals, total GSH and GSH were increased in comparison to C-Ex group. GSH/GSSG ratio decreased abnormally in both exercised groups (p<0.001). Serum cholesterol and uric acid levels increased significantly after exercise (p<0.05). The susceptibility of eryhrocytes to in vitro peroxidation increased in C-Ex and E-Ex animals (p<0.001 and p<0.01, respectively). Elevated malondialdehyde (MDA) concentrtaion in serum attained statistical significance after exercise. However, this elevation was prevented by vitamin E supplementation. Our results indicated that moderate intensive treadmill running exercise was sufficient to result in muscle damage and increases in the susceptibility of erythrocytes to in vitro peroxidation. In addition, dietary supplementation of vitamin E is able to minimize oxidative damage caused by exercise.en_US
dc.identifier.endpage100en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue2en_US
dc.identifier.startpage95en_US
dc.identifier.trdizinid9189
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/9189
dc.identifier.urihttps://hdl.handle.net/11468/25453
dc.identifier.volume29en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEffect of exercise on blood antioxidant status and erythrocyte lipid peroxidation: Role of dietary supplementation of vitamin Een_US
dc.titleEffect of exercise on blood antioxidant status and erythrocyte lipid peroxidation: Role of dietary supplementation of vitamin E
dc.typeOtheren_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu