Neutrophil-to-Lymphocyte Ratio in the Prediction of Microscopic Colitis

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dc.contributor.authorUcmak, Feyzullah
dc.contributor.authorYilmaz, Ahmet
dc.contributor.authorEkin, Nazim
dc.contributor.authorTuncer, Elif Tugba
dc.contributor.authorFirat, Ugur
dc.contributor.authorPalanci, Yilmaz
dc.date.accessioned2024-04-24T17:24:41Z
dc.date.available2024-04-24T17:24:41Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: The aim of this study was to investigate the importance of the neutrophil-to-lymphocyte ratio (NLR) in predicting microscopic colitis (MC) in patients with diarrhea-dominant type irritable bowel syndrome (IBS-D). Material and Method: Between January 1, 2010 and December 31, 2012, 49 patients who fulfilled the Roma III criteria for IBS-D were included in the study. All patients had underwent colonoscopy and colonoscopic biopsy (cecum, ascending, transverse, descending and rectosigmoid sections) to diagnose MC (25 patients with MC). Complete blood count parameters were evaluated in the two groups (IBS-D and MC) using standard methodology. Results: The patients were evaluated in two groups: MC and IBS-D. The groups were similar with respect to age, gender and presence of hypertension. The NLO was significantly higher in the MC group compared to the IBS-D group (2.48 +/- 0.99, 1.92 +/- 0.84; p=0.041, respectively). A cut-off value of 1.86 had a sensitivity of 76% and spesificity of 55% in predicting MC in patients with symptoms of IBS-D. Discussion: A significant association was found between the presence of MC in patients with IBS-D and increased NLR. The NLR may be a useful marker in predicting MC in patients with symptoms of IBS-D.en_US
dc.identifier.doi10.4328/JCAM.3594
dc.identifier.endpage495en_US
dc.identifier.issn1309-0720
dc.identifier.issn1309-2014
dc.identifier.startpage492en_US
dc.identifier.urihttps://doi.org/10.4328/JCAM.3594
dc.identifier.urihttps://hdl.handle.net/11468/19789
dc.identifier.volume6en_US
dc.identifier.wosWOS:000215595200015
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotren_US
dc.publisherDerman Medical Publen_US
dc.relation.ispartofJournal of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIrritable Bowel Syndromeen_US
dc.subjectMicroscopic Colitisen_US
dc.subjectNeutrophil/Lymphocyte Ratioen_US
dc.titleNeutrophil-to-Lymphocyte Ratio in the Prediction of Microscopic Colitisen_US
dc.typeArticleen_US

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