Prognostıc Factors In Testıcular Cancer

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dc.contributor.authorSezgin, Yasin
dc.contributor.authorKarhan, Oğur
dc.contributor.authorBiçer, Abdurrahman
dc.contributor.authorİleri, Serdy
dc.contributor.authorYerlikaya, Halis
dc.contributor.authorTunç, Sezai
dc.contributor.authorAydın, İbrahim
dc.date.accessioned2025-02-22T14:17:58Z
dc.date.available2025-02-22T14:17:58Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: Testicular cancer is the most common cancer in men aged 15-35 years and accounts for 1% of all lifetime male cancers. There are two histologic subtypes: seminoma and nonseminoma. In our study, we aimed to investigate the factors predicting recurrence in early-stage testicular cancer. Materials and Methods: Our study is a retrospective study of early stage testicular cancer admitted to the medical oncololi clinic of our hospital between 2006-2018. During the study, 344 patient files were reviewed and 130 patients who met the study criteria were included in the study. Our primary aim in this study was to investigate the factors predictive of recurrence in early stage testicular cancer. Results: When evaluating PFS in patients with nonseminoma with and without lymphovascular invasion, no median PFS value was reached in either group. However, PFS was worse in patients with LVI (p=0.037). When comparing stage 1 with stage 2 seminoma patients, no median PFS values could be reached, but there was a statistical difference between the two groups in terms of recurrence (p=0.019). Conclusions: In our study, we found no association between tumor size, embryonal carcinoma predominance, tunica albuginea invasion, spermatic cord involvement and tumor marker values and recurrence in nonseminoma germ cell testicular tumors. PFS was shorter in patients with LVI compared to those without LVI. Lymphovascular invasion, spermatic cord involvement, tunica albuginea involvement, and rete testis involvement were not associated with disease recurrence in seminoma patients, whereas higher disease stage predicted the risk of recurrence.en_US
dc.identifier.doi10.18663/tjcl.1445426
dc.identifier.endpage181en_US
dc.identifier.issn2149-8296
dc.identifier.issue2en_US
dc.identifier.startpage176en_US
dc.identifier.trdizinid1248771en_US
dc.identifier.urihttps://doi.org/10.18663/tjcl.1445426
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1248771
dc.identifier.urihttps://hdl.handle.net/11468/30171
dc.identifier.volume15en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Clinics and Laboratoryen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_TR_20250222
dc.subjectPrognosisen_US
dc.subjectdisease-free survivalen_US
dc.subjecttesticular canceren_US
dc.titlePrognostıc Factors In Testıcular Canceren_US
dc.typeArticleen_US

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