Can systemic inflammatory markers predict sperm retrieval with the micro-TESE procedure in patients with non-obstructive azoospermia? A tertiary IVF center experience

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dc.contributor.authorÇöğendez, Ebru
dc.contributor.authorDevranoğlu, Belgin
dc.contributor.authorAras, Alı
dc.contributor.authorKöse, Gökşen Derya Reis
dc.contributor.authorTozkır, Elif
dc.contributor.authorKumru, Pınar
dc.contributor.authorÖzkaya, Enis
dc.date.accessioned2024-04-24T19:13:12Z
dc.date.available2024-04-24T19:13:12Z
dc.date.issued2022
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: We aim to investigate the relationship between the pro-inflammatory mark- ers and sperm retrieval (SR) in microdissection testicular sperm extraction (micro- TESE) procedure in patients with non-obstructive azoospermia (NOA). Material and Methods: This retrospective study was conducted with 318 patients who applied to our in vitro fertilization Unit between April 2017 and December 2020 and underwent micro-TESE for NOA. Patients with (Group 1) and without (Group 2) sperm retrieved were compared in terms of age, infertility duration, body mass index (BMI), hormone profile, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-eosinophil ratio (MER), platelet-to-lymphocyte ratio (PLR), and a new marker of eosinophil-to- lymphocyte ratio (ELR). Results: SR from the micro-TESE procedure was achieved in 183 (57.5%) of 318 patients. Testicular tissue biopsies were performed simultaneously in all cases. There was no statistically significant difference between the groups concerning BMI. When the groups were compared regarding the pro-inflammatory markers, while the NLR, MER, and PLR were found to be statistically higher in Group 2 cases; ELR was similar among groups. Conclusion: The MER, NLR, and PLR were determined to be associated with neg- ative micro-TESE results. Particularly PLR seems to have a poor prognostic value in these patients. A prognostic value of the ELR which was a new biomarker was not determined in SR from the TESE procedure.en_US
dc.identifier.doi10.14744/zkmj.2022.46704
dc.identifier.endpage182en_US
dc.identifier.issn2757-8062
dc.identifier.issue4en_US
dc.identifier.startpage176en_US
dc.identifier.trdizinid1171065
dc.identifier.urihttps://doi.org/10.14744/zkmj.2022.46704
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1171065
dc.identifier.urihttps://hdl.handle.net/11468/28448
dc.identifier.volume53en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofZeynep Kamil medical journal (Online)
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleCan systemic inflammatory markers predict sperm retrieval with the micro-TESE procedure in patients with non-obstructive azoospermia? A tertiary IVF center experienceen_US
dc.titleCan systemic inflammatory markers predict sperm retrieval with the micro-TESE procedure in patients with non-obstructive azoospermia? A tertiary IVF center experience
dc.typeArticleen_US

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