Prematüre bebeklerde nekrotizan enterokolit ve mortalite ilişkisinin değerlendirilmesi
Yükleniyor...
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Van Yüzüncü Yıl Üniversitesi Tıp Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Giriş: Nekrotizan enterokolit, yenidoğan yo ğun bak ım ünitelerinde en sık görülen ciddi gastrointestinal problemlerin başında gelmektedir. Bu çalışmada Nekrotizan enterokolit olguları ve mortalite ilişkisi değerlendirildi. Gereç ve Yöntem: Bu çal ışmada Haziran 2019-Haziran 2021 tarihleri aras ında Çocuk Sa ğlığı ve Hastalıkları Anabilim Dalı Yenidoğan Yoğun Bakım Ünitesi’nde evre II ve üstü Nekrotizan enterokolit tanısı ile takip ve tedavisi yapılan 157 olgu çalışmaya alındı. Bulgular: Olguların %51(80)’i kız ve %49(77)’si erkek, doğum ağırlığı 1147±436 g, gebelik haftası 27.9±3.1 hafta, Anne ya şı 29.2±7.4 ve Anne gebelik sayısı 3.59±2.2 bulundu. Doğum ağırlığına göre dağılım, ≤1000 g %41.4 (65), 1001-1500 g %40.8 (64), 1501-2000 g %13.4 (21), 2001-2500 g %3.2 (5) ve 2501 g ve üstü %1.3(2) bulundu. Olguların gebelik haftasına göre dağılımı ≤27 hafta %42.7 (67), 28-32 hafta %49 (77), 33-36 hafta %7.6 (12) ve 37 hafta ve üstü %0.6 (1) bulundu. Cinsiyet ve anne yaşı ile mortalite arasında istatistiksel olarak anlamlı ilişki bulunmadı. Do ğum a ğırlığı ve gestasyon haftası azaldıkça ve anne gebelik say ısı arttıkça mortalite ve nekrotizan enterokolit sıklığının istatistiksel olarak anlamlı şekilde arttığı bulundu (p<0.05). Sonuç: Yenidoğan dönemindeki prematüre bebeklerde, do ğum ağırlığı ve gestasyon haftas ının azalması, hem nekrotizan enterokolit sıklığında hem de nekrotizan enterokolite ba ğlı mortalite oranında ciddi artışa neden olmaktadır.
Objective: Necrotizing enterocolitis is one of the most common serious gastrointestinal problems in neonatal intensive care units. In this study, the relationship between necrotizing enterocolitis cases and mortality was evaluated. Material and method: This study included 157 cases of necrotizing enterocolitis of stage II and above, who were followed up and treated in Department of Pediatrics, Neonatal Intensive Care Unit between June 2019 and June 2021. Results: 51% (80) of the cases were female and 49% (77) were male, birth weight was 1147±436 g, gestational age was 27.9±3.1 weeks, maternal age was 29.2±7.4, and maternal pregnancy number was 3.59±2.2. Distribution by birth weight, ≤1000 g 41.4%(65), 1001-1500 g 40.8%(64), 1501-2000 g 13.4%(21), 2001-2500 g 3.2%(5) and 2501 g and above 1.3% (2) found. The distribution of the cases according to the week of gestation was found to be ≤27 weeks 42.7% (67), 28-32 weeks 49% (77), 33-36 weeks 7.6% (12), and 37 weeks and above 0.6% (1). There was no statistically significant relationship between gender and maternal age and mortality. As the birth weight and gestational age decreased and the number of maternal pregnancies increased, mortalit y and frequency of necrotizing enterocolitis were found to increase statistically significantly (p<0.05). Conclusion: Decreased birth weight and gestational age in premature infants in the neonatal period cause a serious increase in both the frequency of necrotizing enterocolitis and the mortality rate due to necrotizing enterocolitis.
Objective: Necrotizing enterocolitis is one of the most common serious gastrointestinal problems in neonatal intensive care units. In this study, the relationship between necrotizing enterocolitis cases and mortality was evaluated. Material and method: This study included 157 cases of necrotizing enterocolitis of stage II and above, who were followed up and treated in Department of Pediatrics, Neonatal Intensive Care Unit between June 2019 and June 2021. Results: 51% (80) of the cases were female and 49% (77) were male, birth weight was 1147±436 g, gestational age was 27.9±3.1 weeks, maternal age was 29.2±7.4, and maternal pregnancy number was 3.59±2.2. Distribution by birth weight, ≤1000 g 41.4%(65), 1001-1500 g 40.8%(64), 1501-2000 g 13.4%(21), 2001-2500 g 3.2%(5) and 2501 g and above 1.3% (2) found. The distribution of the cases according to the week of gestation was found to be ≤27 weeks 42.7% (67), 28-32 weeks 49% (77), 33-36 weeks 7.6% (12), and 37 weeks and above 0.6% (1). There was no statistically significant relationship between gender and maternal age and mortality. As the birth weight and gestational age decreased and the number of maternal pregnancies increased, mortalit y and frequency of necrotizing enterocolitis were found to increase statistically significantly (p<0.05). Conclusion: Decreased birth weight and gestational age in premature infants in the neonatal period cause a serious increase in both the frequency of necrotizing enterocolitis and the mortality rate due to necrotizing enterocolitis.
Açıklama
Anahtar Kelimeler
Nekrotizan enterokolit, Yenidoğan, Mortalite, Necrotizing enterocolitis, Newborn, Mortality
Kaynak
Van Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
29
Sayı
1
Künye
Değer, İ., Ertuğrul, S. ve Yolbaş, İ. (2022). Prematüre bebeklerde nekrotizan enterokolit ve mortalite ilişkisinin değerlendirilmesi. Van Tıp Dergisi, 29(1), 108-113.
