Venlafaxine HCl in the treatment of painful peripheral uremic neuropathy: A case report

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dc.contributor.authorKadiroglu A.K.
dc.contributor.authorSit D.
dc.contributor.authorKayabasi H.
dc.contributor.authorYilmaz E.
dc.contributor.authorIsikoglu B.
dc.date.accessioned2024-04-24T18:45:42Z
dc.date.available2024-04-24T18:45:42Z
dc.date.issued2006
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: It is well known that uremia may lead symmetric sensorimotor polyneuropathy that tends to affect the lower limbs compared to upper limbs. It typically involves the legs than the arms. Clinical manifestations include paresthesia, painful dysesthesia, weakness in the legs and arms. The traditional tricyclic antidepressants (TCA) are commonly used in the treatment of painful peripheral polyneuropathy. Venlafaxine is a serotonin-noradrenaline reuptake inhibitor that may have analgesic effect on painful peripheral polyneuropathy. Case Report: Venlafaxine extended release capsule (Effexor 75mg XR, Wyeth) was administered to a 49 years old female patient who has been under hemodialysis therapy for 7 years. She complained of bilateral numbness, pain, pin-pricking and burning in her feet that increasing in the evening. She was also suffered from insomnia for two months. The patient's symptoms were resolved in two weeks after beginning to the therapy but the intensity of pain continued minimaly and the patients demonstrated effective improvements at her insomnia in this period. Venlafaxine was well tolerated and there were no side effects such as nasuea, elevated blood pressure and dizziness. Conclusions: Venlafaxine relieved the symptoms of the uremic polyneuropathy and it was effective in insomnia.en_US
dc.identifier.endpage161en_US
dc.identifier.issn1507-6164
dc.identifier.scopus2-s2.0-33745814339
dc.identifier.scopusqualityN/A
dc.identifier.startpage159en_US
dc.identifier.urihttps://hdl.handle.net/11468/24811
dc.identifier.volume7en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofCase Reports and Clinical Practice Review
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPainful Peripheral Polyneuropathyen_US
dc.subjectUremiaen_US
dc.subjectVenlafaxine Hclen_US
dc.titleVenlafaxine HCl in the treatment of painful peripheral uremic neuropathy: A case reporten_US
dc.titleVenlafaxine HCl in the treatment of painful peripheral uremic neuropathy: A case report
dc.typeArticleen_US

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