Evaluation of febrile neutropenic patients hospitalized in a hematology clinic

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dc.contributor.authorGörük, Mücahit
dc.contributor.authorDal, Mehmet Sinan
dc.contributor.authorDal, Tuba
dc.contributor.authorKarakuş, Abdullah
dc.contributor.authorTekin, Recep
dc.contributor.authorÖzcan, Nida
dc.contributor.authorAyyıldız, Orhan
dc.contributor.orcid0000-0003-2090-4392
dc.date.accessioned2024-04-24T17:56:06Z
dc.date.available2024-04-24T17:56:06Z
dc.date.issued2015
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractObjective: To evaluate the febrile neutropenic patients with hematological malignancies hospitalized in hematology clinic with poor hygiene standards. Methods: A total of 124 patients with hematological malignancies (69 male, 55 female) hospitalized in hematology clinic with poor hygiene conditions depending on hospital conditions, between January 2007 and December 2010, were evaluated, retrospectively. Results: In this study, 250 febrile neutropenia episodes developing in 124 hospitalized patients were evaluated. Of the patients, 69 were men (56%) and 55 women (44%). A total of 40 patients (32%) had acute myeloid leukemia, 25 (20%) acute lymphoblastic leukemia, 19 (15%) non-Hodgkin's lymphoma, 10 (8%) multiple myeloma, and 8 (8%) chronic myeloid leukemia. In our study, 56 patients (22%) were diagnosed as pneumonia, 38 (15%) invasive aspergillosis, 38 (15%) sepsis, 16 (6%) typhlitis, 9 (4%) mucormycosis, and 4 (2%) urinary tract infection. Gram-positive cocci were isolated from 52% (n = 20), while Gram-negative bacilli 42% (n = 16) and yeasts from 6% (n = 2) of the sepsis patients, respectively. The most frequently isolated Gram-positive bacteria were methicillin-resistant coagulase-negative staphylococci (n = 18), while the most frequently isolated Gram-negative bacteria was Escherichia coli (n = 10). Conclusions: Febrile neutropenia is still a problem in patients with hematological malignancies. The documentation of the flora and detection of causative agents of infections in each unit would help to decide appropriate empirical therapy. Infection control procedures should be applied for preventing infections and transmissions.en_US
dc.identifier.citationGörük, M., Dal, M. S., Dal, T., Karakuş, A., Tekin, R., Özcan, N. ve diğerleri. (2015). Evaluation of febrile neutropenic patients hospitalized in a hematology clinic. Asian Pacific Journal of Tropical Biomedicine, 5(12), 1051-1054.
dc.identifier.doi10.1016/j.apjtb.2015.09.014
dc.identifier.endpage1054en_US
dc.identifier.issn2221-1691
dc.identifier.issue12en_US
dc.identifier.scopus2-s2.0-84959093473
dc.identifier.scopusqualityQ2
dc.identifier.startpage1051en_US
dc.identifier.urihttps://doi.org/10.1016/j.apjtb.2015.09.014
dc.identifier.urihttps://hdl.handle.net/11468/23290
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S2221169115002269?via%3Dihub
dc.identifier.volume5en_US
dc.indekslendigikaynakScopus
dc.institutionauthorGörük, Mücahit
dc.institutionauthorDal, Mehmet Sinan
dc.institutionauthorKarakuş, Abdullah
dc.institutionauthorTekin, Recep
dc.institutionauthorÖzcan, Nida
dc.institutionauthorAyyıldız, Orhan
dc.language.isoenen_US
dc.publisherHainan Medical Universityen_US
dc.relation.ispartofAsian Pacific Journal of Tropical Biomedicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFebrile neutropeniaen_US
dc.subjectHematological malignancyen_US
dc.subjectInfectionsen_US
dc.subjectLeukemiaen_US
dc.subjectMultiple myelomaen_US
dc.titleEvaluation of febrile neutropenic patients hospitalized in a hematology clinicen_US
dc.titleEvaluation of febrile neutropenic patients hospitalized in a hematology clinic
dc.typeArticleen_US

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