Evaluation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with lichen planus

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dc.contributor.authorAn, İsa
dc.contributor.authorÖztürk, Murat
dc.contributor.authorUçmak, Derya
dc.date.accessioned2024-04-24T19:11:35Z
dc.date.available2024-04-24T19:11:35Z
dc.date.issued2019
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: In recent years, neutrophil / lymphocyte ratio (NLR), platelet / lymphocyte ratio (PLR) and mean platelet volume (MPV) has been shown to be important indicators of systemicinflammation. Studies have shown that NLR and PLR are higher and that MPV is lower in lichen planus patients compared to the control group. In this study, NLR, PLR and MPV values of lichen planus patients were calculated and investigated whether these parameters were related to nail and oral mucosal involvement.Material and Methods: Eighty one patients with lichen planus without any systemic, infectious and autoimmune disease were included in this study while 81 patients who were admitted to the outpatient clinic for any non-inflammatory condition and whom had blood picture were included in the study as control group.Results: There was no statistically significant difference between neutrophil count, lymphocyte count, leukocyte count, platelet count, NLR and PLR values in LP patients and control group (p> 0.05). MPV value of LP patients had a mean of 8.10 ± 1.40 , and controls had a mean of 7.21 ± 1.45, and the difference was statistically significant (p <0.001). There wasn’t statistically significant relationship between neutrophil count, lymphocyte count, leukocyte count, platelet count, NLR, PLR and MPV values and nail and oral mucosa involvement (p> 0.05).Conclusion: It can be concluded that NLR and PLR were not suitable parameters to show inflammation in LP. The significant higher values of MPV in LP patients suggests that it may be used as a better marker of inflammation in LP patients than NLR and PLR. Nevertheless, the lack of significant association of MPV with nail involvement and oral mucosal involvement may restrict clinical use of it in LP.en_US
dc.identifier.doi10.5455/annalsmedres.2018.08.169
dc.identifier.endpage164en_US
dc.identifier.issn2636-7688
dc.identifier.issue2en_US
dc.identifier.startpage161en_US
dc.identifier.trdizinid315692
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2018.08.169
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/315692
dc.identifier.urihttps://hdl.handle.net/11468/28100
dc.identifier.volume26en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with lichen planusen_US
dc.titleEvaluation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with lichen planus
dc.typeArticleen_US

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