Insulin sensivitiy, $beta$ cell function and serum lipid levels in Helicobacter pylori positive, non-obese, young adult males

Basit Öğe Kaydı
dc.contributor.authorBahceci, Mithat
dc.contributor.authorTuzcu, Alpaslan
dc.contributor.authorCanoruç, Fikri
dc.contributor.authorDursun, Mehmet
dc.contributor.authorYılmaz, Şerif
dc.date.accessioned2024-04-24T18:58:39Z
dc.date.available2024-04-24T18:58:39Z
dc.date.issued2004
dc.departmentDicle Üniversitesien_US
dc.description.abstractIt is not clear whether Helicobacter pylori (Hp) infection affects insulin levels and insulin sensitivity. We aimed to determine insulin sensitivity and beta cell function, and to evaluate serum lipids in subjects with and without Hp infection. Eighty non-obese young adult males, 40 of whom were Hp positive and 40 were negative, were included in the study. Two endoscopic biopsy specimens were obtained from each subject. Height, weight and waist-hip circumference were measured, and body mass index (BMI) was calculated. Serum glucose, total, HDL, LDL and VLDL-cholesterol and triglyceride levels were determined. Body fat mass and percentage were determined by bioelectric impedance. Serum insulin levels were measured by the RIA method. HOMA was used as an index of pancreatic beta cell function and insulin sensitivity. The independent-t test was used in the comparison of results. Age, BMI, waist and hip circumferences, and fat percentages did not exhibit any statistical differences. Mean HOMA-B [111.7, in Hp(+) and 112.0 in Hp(-) subjects] and HOMA-S [67.7 in Hp(+) and 60.7 Hp(-) subjects] did not differ amoung the groups. The lipid and aminotransferase levels of the 2 groups were also similar. Conclusion: Hp infection is not associated with impairment of insulin sensitivity and deterioration of the glucose metabolism. It seems to be metabolically neutral in terms of serum lipids and aminotransferase levels.en_US
dc.identifier.endpage107en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue2en_US
dc.identifier.startpage103en_US
dc.identifier.trdizinidTRDizinIdYok
dc.identifier.urihttps://hdl.handle.net/11468/25886
dc.identifier.volume34en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleInsulin sensivitiy, $beta$ cell function and serum lipid levels in Helicobacter pylori positive, non-obese, young adult malesen_US
dc.titleInsulin sensivitiy, $beta$ cell function and serum lipid levels in Helicobacter pylori positive, non-obese, young adult males
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu