Comparison of IMA, YKL-40, EN-RAGE, and AIM levels in maternal blood and cord blood in patients with preeclampsia

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dc.authorid0000-0001-9142-6127en_US
dc.authorid0000-0001-7982-1407en_US
dc.authorid0000-0003-2583-2770en_US
dc.authorid0000-0001-8468-7038en_US
dc.authorid0000-0002-4215-1371en_US
dc.authorid0000-0002-1680-907Xen_US
dc.authorid0000-0002-5491-8138en_US
dc.contributor.authorFındık, Fatih Mehmet
dc.contributor.authorİçen, Mehmet Sait
dc.contributor.authorTunç, Senem Yaman
dc.contributor.authorGündüz, Reyhan
dc.contributor.authorAğaçayak, Elif
dc.contributor.authorEvsen, Mehmet Sıddık
dc.contributor.authorSatıcı, Ömer
dc.date.accessioned2023-06-15T13:11:19Z
dc.date.available2023-06-15T13:11:19Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalıen_US
dc.description.abstractAim: Preeclampsia and severe preeclampsia are among the most significant causes of maternal mortality. Preeclampsia’s pathogenesis is not fully understood, and it is a disease with early diagnosis and treatment possibilities. In this study, we aimed to investigate the levels of IMA, YKL-40, EN-RAGE, and AIM in maternal and cord blood. The results will ideally shed light on preeclampsia’s pathogenesis and early diagnosis. Methods: The study was conducted with the following three groups: a severe preeclampsia group (group 1), a preeclampsia group (group 2), and a control group (group 3). IMA, YKL-40, EN-RAGE, and AIM levels were measured in all patients across the groups using blood taken from the mothers before delivery and from the cords during delivery. Statistically descriptive analyses were performed. Specifically, a one-way analysis of variance was performed on group variables, and a Tukey test was used to determine the differences between the groups. Results: The mean age was similar across all groups. The gestational week at delivery was low for the severe preeclampsia group (p=0.001). The IMA and YKL-40 levels in the maternal and cord blood were the same between the groups. The EN-RAGE levels in the maternal blood were found to be significantly higher in the control group (p=0.000). While the AIM levels in the maternal blood were high in the control group (p=0.001), they were significantly lower in the cord blood in the control group (p=0.029). Conclusion: EN-RAGE and AIM levels are parameters that can be used in the early diagnosis of preeclampsia and severe preeclampsia.en_US
dc.identifier.citationFındık, M. F., İçen, M. S., Tunç, S. Y., Gündüz, R., Ağaçayak, E., Evsen, M. S. ve diğerleri. (2023). Comparison of IMA, YKL-40, EN-RAGE, and AIM levels in maternal blood and cord blood in patients with preeclampsia. Experimental Biomedical Research, 6(2), 153-159.en_US
dc.identifier.doi10.30714/j-ebr.2023.180
dc.identifier.endpage159en_US
dc.identifier.issn2618-6454
dc.identifier.issue2en_US
dc.identifier.startpage153en_US
dc.identifier.trdizinid1175437
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1175437
dc.identifier.urihttps://hdl.handle.net/11468/12052
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1175437
dc.identifier.volume6en_US
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorFındık, Fatih Mehmet
dc.institutionauthorİçen, Mehmet Sait
dc.institutionauthorTunç, Senem Yaman
dc.institutionauthorGündüz, Reyhan
dc.institutionauthorAğaçayak, Elif
dc.institutionauthorEvsen, Mehmet Sıddık
dc.institutionauthorSatıcı, Ömer
dc.language.isoenen_US
dc.relation.ispartofExperimental Biomedical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleComparison of IMA, YKL-40, EN-RAGE, and AIM levels in maternal blood and cord blood in patients with preeclampsiaen_US
dc.titleComparison of IMA, YKL-40, EN-RAGE, and AIM levels in maternal blood and cord blood in patients with preeclampsia
dc.typeArticleen_US

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