Risk of Helicobacter pylori infection in newborn babies of Helicobacter pylori-positive pregnant women

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dc.contributor.authorDursun M.
dc.contributor.authorGoral V.
dc.contributor.authorSimsek H.
dc.contributor.authorYukselen V.
dc.contributor.authorHascelik G.
dc.contributor.authorCanoru F.
dc.date.accessioned2024-04-24T17:58:52Z
dc.date.available2024-04-24T17:58:52Z
dc.date.issued1998
dc.departmentDicle Üniversitesien_US
dc.description.abstractHelicobacter pylori (H.pylori) is one of the rare organisms that can maintain its life in acidic condition of stomach. A number of studies indicate that it is closely inked to mainly duodenal ulcer as well as peptic ulcer, non-ulcer dyspepsy, gastric cancer and MALT lymphoma. The aim of our study was to determine whether newborn infants of H.pylori-positive mothers are at risk of H.pylori infection A total of 48 mother and their newborn babies were included in the study. Soon after the birth, blood specimens were taken from both mothers and babies. Anti-H.pylori IgG was examined from the blood of the mothers by ELISA. The blood of babies of mothers with anti- H.pylori IgG-positive was investigated for both anti-H.pylori IgG and anti- H.pylori IgA. In 36 (75.0%) of 48 women included in the study, anti-H.pylori IgG antibody was found as positive. In addition, anti-H.pylori IgG was determined to be positive in 32 (89.0%) of 36 babies whose mothers were positive for anti-H.pylori IgG. These 32 babies whose anti-H.pylori IgG was positive were examined for anti-H.pylori IgA. In 3 babies (9.4%), it was found to be positive (p<0.01). In conclusion, owing to IgG's feature of being able to transmit through the placenta, it is clear that the presence of anti- H.pylori IgG in the serum of babies whose mothers are positive for anti- H.pylori IgG antibody cannot be an indicator of H.pylori infection. Determination of anti-H.pylori IgA antibody as positive is important and statistically significant (p<0.01). According to the results of this study, it can be said that at least the possibility of vertical transmission may exist.en_US
dc.identifier.endpage39en_US
dc.identifier.issn1300-4948
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-0031859175en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage36en_US
dc.identifier.urihttps://hdl.handle.net/11468/24136
dc.identifier.volume9en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHelicobacter Pylorien_US
dc.subjectVertical Transmissionen_US
dc.titleRisk of Helicobacter pylori infection in newborn babies of Helicobacter pylori-positive pregnant womenen_US
dc.title.alternativeHelicobacter pylori pozitif annelerin bebeklerinde helicobacter pylori enfeksiyonu riski (vertikal gecis)en_US
dc.typeArticleen_US

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