Effect of exercise on blood antioxidant status and erythrocyte lipid perodixation: Role of dietary supplementation of vitamin E

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dc.contributor.authorKelle M.
dc.contributor.authorDiken H.
dc.contributor.authorSermet A.
dc.contributor.authorAtmaca M.
dc.contributor.authorTumer C.
dc.date.accessioned2024-04-24T18:44:01Z
dc.date.available2024-04-24T18:44:01Z
dc.date.issued1999
dc.departmentDicle Üniversitesien_US
dc.description.abstractWe tested the effects of moderate physical exercise on the blood antioxidant capacity and erythrocyte lipid peroxidation in 21 Wistar albino rats. Erythrocyte superoxide dismutase (SOD) activity increased significantly (p<0.05) in control exercised animals (C-Ex), but catalase activity did not change. SOD activity was decreased by dietary supplementation of vitamin E (p<0.05). In vitamin E supplemented group (E-Ex), catalase activity was reduced in comparison to C-Ex group. Total glutathione (total GSH) level was unaffected by the exercise. However, significant reduction was observed in reduced glutathione (GSH), whereas oxidized glutathione (GSSG) increased (p<0.01 and p<0.001, respectively). In E-Ex animals, total GSH and GSH were increased in comparison to C-Ex group. GSH/GSSG ratio decreased abnormally in both exercised groups (p<0.001). Serum cholesterol and uric acid levels increased significantly after exercise (p<0.05). The susceptibility of erythrocytes to in vitro peroxidation increased in C-Ex and E-Ex animals (p<0.001 and p<0.01, respectively). Elevated malondialdehyde (MDA) concentration in serum attained statistical significance after exercise. However, this elevation was prevented by vitamin E supplementation. Our results indicated that moderate intensive treadmill running exercise was sufficient to result in muscle damage and increases in the susceptibility of erythrocytes to in vitro peroxidation. In addition, dietary supplementation of vitamin E is able to minimize oxidative damage caused by exercise.en_US
dc.identifier.endpage100en_US
dc.identifier.issn1300-0144
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0033067149
dc.identifier.scopusqualityQ1
dc.identifier.startpage95en_US
dc.identifier.urihttps://hdl.handle.net/11468/24514
dc.identifier.volume29en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectErythrocyteen_US
dc.subjectLipid Peroxidationen_US
dc.subjectModerate Exerciseen_US
dc.subjectVitamin Een_US
dc.titleEffect of exercise on blood antioxidant status and erythrocyte lipid perodixation: Role of dietary supplementation of vitamin Een_US
dc.titleEffect of exercise on blood antioxidant status and erythrocyte lipid perodixation: Role of dietary supplementation of vitamin E
dc.typeArticleen_US

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