Evaluation of endothelial functions of psoriasis patients by flow mediated dilatation method

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dc.contributor.authorOylumlu M.
dc.contributor.authorYüksel M.
dc.contributor.authorYıldız A.
dc.contributor.authorUçmak D.
dc.contributor.authorAkkurt Z.M.
dc.contributor.authorKaramanlıoğlu M.
dc.contributor.authorAydın M.
dc.date.accessioned2024-04-24T18:43:46Z
dc.date.available2024-04-24T18:43:46Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: Flow mediated dilatation (FMD) is a good sonographic indicator of early atherosclerotic changes which reflects endothelial functions by measuring dilatation of peripheral arteries in response to physical stressors. In this study, we aimed to measure FMD on brachial artery of patients with psoriasis which reflects endothelial dysfunction and compare to that of healthy volunteers. Methods: 30 patients with psoriasis and 31 control subjects matched in terms of age, gender, and demographic characteristics were included to this observational, case-control study. FMD was measured on the nondominant arm of the subjects by using sonographic techniques. Results: The patients and controls were similar in terms of sex, gender, smoking, arterial blood pressure, and body mass index. FMD values, reflecting endothelial functions, were tended to be lower in psoriasis group than healthy controls; however this difference was not statistically significant (7.7 ± 3.1 vs. 8.6 ± 2.8, respectively; p = 0.247). Conclusion: These results support that presence of psoriasis is not a risk factor for future cardiovascular disease development. Prospective, multi-center, large scale studies including control group are needed in order to clarify this issue. © 2012 Düzce Medical Journal.en_US
dc.identifier.endpage48en_US
dc.identifier.issn1307-671X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84955458615en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage45en_US
dc.identifier.urihttps://hdl.handle.net/11468/24360
dc.identifier.volume17en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.publisherDuzce University Medical Schoolen_US
dc.relation.ispartofDuzce Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndothelialen_US
dc.subjectFlow-Mediated Dilationen_US
dc.subjectPsoriasisen_US
dc.titleEvaluation of endothelial functions of psoriasis patients by flow mediated dilatation methoden_US
dc.title.alternativePsoriyazis Hastalarinda Endotel Fonksiyonlarinin Akim Aracili Dilatasyon Yöntemi Ile Değerlendirilmesien_US
dc.typeArticleen_US

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