The effect of exogen glutathione administration on the gastric mucosal barrier in rats under stress

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dc.contributor.authorKanay Z.
dc.contributor.authorSert C.
dc.contributor.authorIsik B.
dc.contributor.authorKurt D.
dc.contributor.authorGuzel C.
dc.contributor.authorMete N.
dc.date.accessioned2024-04-24T17:58:52Z
dc.date.available2024-04-24T17:58:52Z
dc.date.issued1998
dc.departmentDicle Üniversitesien_US
dc.description.abstractWe investigated the effect of glutathione (GSH) on the gastric mucosal barrier of rats under stress. Twenty two swiss Albino rats weighing between 150-200 g were used and stress was induced by cold and immobilisation. GSH was administered in 300 mg/kg doses to the study group and oral saline was given to a control group. Mucus and phospholipid levels of the gastric mucosal barrier were then measured using come and Baur's methods. These important components of the gastric mucosal barrier were found to be decreased (p<0.05), but levels were higher in rats given GSH than in the control group (p<0.01, p<0.05 respectively). To conclude, GSH was found to be effective in preventing gastric mucosal barrier damage caused by stress.en_US
dc.identifier.endpage228en_US
dc.identifier.issn1300-4948
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-0031665969en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage226en_US
dc.identifier.urihttps://hdl.handle.net/11468/24138
dc.identifier.volume9en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGasric Mucosal Barrieren_US
dc.subjectGlutathioneen_US
dc.subjectStressen_US
dc.titleThe effect of exogen glutathione administration on the gastric mucosal barrier in rats under stressen_US
dc.title.alternativeStres uygulanan ratlarda eksojen glutatyon uygulamasinin mide mukozal bariyeri uzerindeki etkilerien_US
dc.typeArticleen_US

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